Quantification of functional abilities in Rett syndrome: a comparison between stages III and IV

dc.contributor.authorMonteiro, Carlos B. M.
dc.contributor.authorSavelsbergh, Geert J. P.
dc.contributor.authorSmorenburg, Ana R. P.
dc.contributor.authorGraciani, Zodja
dc.contributor.authorTorriani-Pasin, Camila
dc.contributor.authorAbreu, Luiz Carlos de
dc.contributor.authorValenti, Vitor Engrácia [UNESP]
dc.contributor.authorKok, Fernando
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionVrije Univ Amsterdam
dc.contributor.institutionBurke Cornell Med Res Inst
dc.contributor.institutionSch Med ABC
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-12-03T13:10:28Z
dc.date.available2014-12-03T13:10:28Z
dc.date.issued2014-01-01
dc.description.abstractWe aimed to evaluate the functional abilities of persons with Rett syndrome (RTT) in stages III and IV. The group consisted of 60 females who had been diagnosed with RTT: 38 in stage III, mean age (years) of 9.14, with a standard deviation of 5.84 (minimum 2.2/maximum 26.4); and 22 in stage IV, mean age of 12.45, with a standard deviation of 6.17 (minimum 5.3/maximum 26.9). The evaluation was made using the Pediatric Evaluation of Disability Inventory, which has 197 items in the areas of self-care, mobility, and social function. The results showed that in the area of self-care, stage III and stage IV RTT persons had a level of 24.12 and 18.36 (P=0.002), respectively. In the area of mobility, stage III had 37.22 and stage IV had 14.64 (P<0.001), while in the area of social function, stage III had 17.72 and stage IV had 12.14 (P=0.016). In conclusion, although persons with stage III RTT have better functional abilities when compared with stage IV, the areas of mobility, self-care, and social function are quite affected, which shows a great functional dependency and need for help in basic activities of daily life.en
dc.description.affiliationUniv Sao Paulo, Escola Artes Ciencias & Humanidades, BR-03828000 Sao Paulo, Brazil
dc.description.affiliationVrije Univ Amsterdam, Fac Human Movement Sci, MOVE Res Inst Amsterdam, Amsterdam, Netherlands
dc.description.affiliationBurke Cornell Med Res Inst, White Plains, NY USA
dc.description.affiliationUniv Sao Paulo, Dept Neurol, BR-03828000 Sao Paulo, Brazil
dc.description.affiliationUniv Sao Paulo, Motor Behav Lab, BR-03828000 Sao Paulo, Brazil
dc.description.affiliationSch Med ABC, Dept Morphol & Physiol, Lab Sci Writing, Santo Andre, Brazil
dc.description.affiliationUNESP, Fac Philosophy & Sci, Dept Speech Language & Hearing Therapy, Marilia, Brazil
dc.description.affiliationUnespUNESP, Fac Philosophy & Sci, Dept Speech Language & Hearing Therapy, Marilia, Brazil
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipIdFAPESP: 14/00320-8
dc.format.extent1213-1222
dc.identifierhttp://dx.doi.org/10.2147/NDT.S57333
dc.identifier.citationNeuropsychiatric Disease And Treatment. Albany: Dove Medical Press Ltd, v. 10, p. 1213-1222, 2014.
dc.identifier.doi10.2147/NDT.S57333
dc.identifier.fileWOS000338431000002.pdf
dc.identifier.issn1178-2021
dc.identifier.urihttp://hdl.handle.net/11449/112162
dc.identifier.wosWOS:000338431000002
dc.language.isoeng
dc.publisherDove Medical Press Ltd
dc.relation.ispartofNeuropsychiatric Disease And Treatment
dc.relation.ispartofjcr2.195
dc.rights.accessRightsAcesso aberto
dc.sourceWeb of Science
dc.subjectRett syndromeen
dc.subjectdisability evaluationen
dc.subjectself-careen
dc.subjectmobility limitationen
dc.titleQuantification of functional abilities in Rett syndrome: a comparison between stages III and IVen
dc.typeArtigo
dcterms.rightsHolderDove Medical Press Ltd
unesp.author.orcid0000-0001-7477-3805[7]
unesp.author.orcid0000-0002-7618-2109[6]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Filosofia e Ciências, Maríliapt

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