Cissus quadrangularis (Linn) (Uva velve) and phyllanthus reticulatus poir (Linn) (Pancolin) in wound healing

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dc.contributor.authorCharas Dos Santos, Ivan Felismino [UNESP]
dc.contributor.authorNhambirre, André
dc.contributor.authorBata Bambo, Otilia [UNESP]
dc.contributor.authorMota Cardoso, José Manuel [UNESP]
dc.contributor.institutionUniversidad Eduardo Mondlane
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.date.accessioned2022-04-28T19:01:44Z
dc.date.available2022-04-28T19:01:44Z
dc.date.issued2015-07-01
dc.description.abstractIntroduction: Cissus quadrangularis (Linn) has healing, analgesia and antiinflammatory effects. Phyllanthus reticulatus Poir (Linn) is used for treating skin wounds, burns and ulcers. Objectives: to compare the effectiveness of C. quandrangularis and P. reticulatus in wounds healing surgically induced in skin of guinea pigs, evaluating the healing time, microscopic and macroscopic healing variations and contamination degree. Methods: Was used in study 30 health guinea pigs, males, six months old, with mean weight of 650 grams. Three wounds were promoted in each animal in the dorsal region and the wound was treated, daily, with C. quandrangularis, saline solution 0.9% and with P. reticulatus. The biopsies were performed in Group I on the seventh day after the surgery, Group II on the fourteenth day and the Group III on the twenty-first day after the surgery and sent to histopathologycal evaluation. Results: on the seventh day of treatment the wounds which treated with C. quadrangularis were observed granulation tissue, while wounds treated with P. reticulatus were observed on the ninth day after. No healing significant difference occurred between the treatments. During the study was observed predominance of neutrophils in all wounds of all groups, more evident in those treated with C. quandrangularis. Conclusion: The wounds which treated with C. quandrangularis healed faster and showed less contamination degree than treated with P. reticulatus.en
dc.description.affiliationUniversidad Eduardo Mondlane
dc.description.affiliationUniversidad Estadual Paulista
dc.description.affiliationUnespUniversidad Estadual Paulista
dc.format.extent348-357
dc.identifier.citationRevista Cubana de Plantas Medicinales, v. 20, n. 3, p. 348-357, 2015.
dc.identifier.issn1028-4796
dc.identifier.scopus2-s2.0-84946556099
dc.identifier.urihttp://hdl.handle.net/11449/220491
dc.language.isospa
dc.relation.ispartofRevista Cubana de Plantas Medicinales
dc.sourceScopus
dc.subjectHealing evolution
dc.subjectPhitotherapy
dc.subjectSkin lesion
dc.titleCissus quadrangularis (Linn) (Uva velve) and phyllanthus reticulatus poir (Linn) (Pancolin) in wound healingen
dc.titleCissus quadrangularis (Linn) (Uva Velve) y Phyllanthus reticulatus Poir (Linn) (Pancolin) en la cicatrización de heridases
dc.typeArtigo

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