Evaluation of crystallized biosilicate in the reconstruction of calvarial defects

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dc.contributor.authorAzenha, Marcelo Rodrigues [UNESP]
dc.contributor.authorde Lacerda, Suzie Aparecida
dc.contributor.authorMarão, Heloísa Fonseca [UNESP]
dc.contributor.authorFilho, Oscar Peitl
dc.contributor.authorFilho, Osvaldo Magro [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Federal de São Carlos (UFSCar)
dc.date.accessioned2015-12-07T15:35:06Z
dc.date.available2015-12-07T15:35:06Z
dc.date.issued2015
dc.description.abstractThe objective of this study was to assess the bone repair process of crystallized Biosilicate in surgically created defects on rats' calvaria. This biomaterial was recently developed for odontological use. We used fifteen rats (rattus norvegicus albinus, Wistar), and two 5 mm surgical defects were performed on each of them; the defects were made with trephine drill on the calvarium region prior to the biomaterial placement. Groups were divided as follows: Group 1-defect filled with clot; Group 2-defect filled with crystallized Biosilicate. After 7, 14 and 28 days the animals were killed, the parts were retrieved and slides were prepared for histological studies. Bone formation was satisfactory in all groups, with direct contact between biomaterial surface and bone and absence of infection signs. The 28 days periods showed better results, and statistically significant difference between Clot Group (90.2 %) and Biosilicate (58 %; p = 0.002) was seen, regarding presence of bone tissue on the surgical defects. Our study revealed that defects filled with clot present better results on bone formation compared to crystallized Biosilicate, which is considered a biocompatible material with favorable osteoconductive properties.en
dc.description.affiliationDentistry School of Ribeirão Preto, Stomatology Department, Universidade de São Paulo (USP), Avenida do café s/n, Bairro Monte Alegre, Ribeirão Preto, Brazil ; Dentistry School of Araçatuba, Universidade Estadual Paulista (UNESP), São Paulo, Brazil.
dc.description.affiliationDentistry School of Ribeirão Preto, Stomatology Department, Universidade de São Paulo (USP), Avenida do café s/n, Bairro Monte Alegre, Ribeirão Preto, Brazil.
dc.description.affiliationDentistry School of Araçatuba, Universidade Estadual Paulista (UNESP), São Paulo, Brazil.
dc.description.affiliationUniversidade Federal de São Carlos (UFSCAR), São Paulo, Brazil.
dc.description.affiliationUnespDentistry School of Ribeirão Preto, Stomatology Department, Universidade de São Paulo (USP), Avenida do café s/n, Bairro Monte Alegre, Ribeirão Preto, Brazil ; Dentistry School of Araçatuba, Universidade Estadual Paulista (UNESP), São Paulo, Brazil.
dc.description.affiliationUnespDentistry School of Araçatuba, Universidade Estadual Paulista (UNESP), São Paulo, Brazil.
dc.format.extent659-665
dc.identifierhttp://dx.doi.org/10.1007/s12663-015-0755-8
dc.identifier.citationJournal Of Maxillofacial And Oral Surgery, v. 14, n. 3, p. 659-665, 2015.
dc.identifier.doi10.1007/s12663-015-0755-8
dc.identifier.issn0972-8279
dc.identifier.pmcPMC4511902
dc.identifier.pubmed26225059
dc.identifier.urihttp://hdl.handle.net/11449/131414
dc.language.isoeng
dc.publisherSpringer
dc.relation.ispartofJournal Of Maxillofacial And Oral Surgery
dc.rights.accessRightsAcesso restrito
dc.sourcePubMed
dc.subjectBioglassen
dc.subjectBiomaterialen
dc.subjectBiosilicateen
dc.titleEvaluation of crystallized biosilicate in the reconstruction of calvarial defectsen
dc.typeArtigo
dcterms.rightsHolderSpringer
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Odontologia, Araçatubapt

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Artigos - Cirurgia e Clínica Integrada - FOA