Importância do modelo animal para testar hipóteses sobre a fisiopatologia do binômio diabetes e incontinência urinária feminina

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dc.contributor.authorMarini, Gabriela [UNESP]
dc.contributor.authorPiculo, Fernanda [UNESP]
dc.contributor.authorBarbosa, Angélica Mércia Pascon [UNESP]
dc.contributor.authorDamasceno, Débora Cristina [UNESP]
dc.contributor.authorMatheus, Selma Maria Michelin [UNESP]
dc.contributor.authorRudge, Marilza Vieira Cunha [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:26:20Z
dc.date.available2014-05-27T11:26:20Z
dc.date.issued2011-12-23
dc.description.abstractAims: To discuss the importance of studying animal models to test hypotheses about the mechanisms of urinary continence and pathophysiology of diabetes and urinary incontinence. Source of Data: A literature review was conducted in PubMed and SciELO. The key words used were diabetes, urinary incontinence, urethra, human and rats. Summary of Findings: There is a strong relation between the genesis of urinary incontinence and diabetes mellitus. Due to the similarity of normal distribution of skeletal muscle and urethra anatomy between humans and rats, these animal models have been used in current research about these disorders. Conclusions: The use of rats as an animal model is suitable for experimental studies that test hypotheses about the mechanisms of continence and pathophysiology of the binomial diabetes mellitus and urinary incontinence, thus enabling solutions of great value in clinical practice.en
dc.description.affiliationLaboratório de Pesquisa Experimental de Ginecologia e Obstetrícia Departamento de Ginecologia e Obstetrícia Faculdade de Medicina de Botucatu, Universidade Estadual Paulista, São Paulo
dc.description.affiliationDepartamento de Anatomia Instituto de Biociências de Botucatu Universidade Estadual Paulista, São Paulo
dc.description.affiliationUnespLaboratório de Pesquisa Experimental de Ginecologia e Obstetrícia Departamento de Ginecologia e Obstetrícia Faculdade de Medicina de Botucatu, Universidade Estadual Paulista, São Paulo
dc.description.affiliationUnespDepartamento de Anatomia Instituto de Biociências de Botucatu Universidade Estadual Paulista, São Paulo
dc.format.extent191-195
dc.identifierhttp://revistaseletronicas.pucrs.br/ojs/index.php/scientiamedica/article/view/9230
dc.identifier.citationScientia Medica, v. 21, n. 4, p. 191-195, 2011.
dc.identifier.file2-s2.0-83755207671.pdf
dc.identifier.issn1806-5562
dc.identifier.issn1980-6108
dc.identifier.lattes6758680388835078
dc.identifier.orcid0000-0002-9227-832X
dc.identifier.scopus2-s2.0-83755207671
dc.identifier.urihttp://hdl.handle.net/11449/73082
dc.language.isopor
dc.relation.ispartofScientia Medica
dc.relation.ispartofsjr0,123
dc.relation.ispartofsjr0,123
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectAnimal
dc.subjectDiabetes mellitus/physiopathology
dc.subjectFemale
dc.subjectModels
dc.subjectMuscle
dc.subjectRats
dc.subjectStriated/anatomy histology
dc.subjectUrethra/anatomy histology
dc.subjectUrinary incontinence/physiopathology
dc.subjectdiabetes mellitus
dc.subjectdisease association
dc.subjectdisease model
dc.subjectexperimental rat
dc.subjectexperimental study
dc.subjectfemale
dc.subjecthuman
dc.subjectmorphology
dc.subjectnonhuman
dc.subjectpathophysiology
dc.subjectreview
dc.subjectskeletal muscle
dc.subjectsystematic review
dc.subjecturethra
dc.subjecturine incontinence
dc.titleImportância do modelo animal para testar hipóteses sobre a fisiopatologia do binômio diabetes e incontinência urinária femininapt
dc.title.alternativeImportance of animal model to test hypotheses about the pathophysiology of the binomial diabetes and female urinary incontinenceen
dc.typeArtigo
dcterms.licensehttp://revistaseletronicas.pucrs.br/ojs/index.php/scientiamedica/about/editorialPolicies#openAccessPolicy
unesp.author.lattes6758680388835078
unesp.author.lattes2604323526583616[3]
unesp.author.orcid0000-0002-9227-832X[6]
unesp.author.orcid0000-0003-0817-9511[3]
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Biociências, Botucatupt
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt

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Artigos - Ginecologia e Obstetrícia - FMB
Artigos - Anatomia - IBB