Study of virulence factors in coagulase-negative staphylococci isolated from newborns

Página do item simplificado
dc.contributor.authorCunha, Maria de Lourdes Ribeiro de Souza da [UNESP]
dc.contributor.authorRugolo, Ligia Maria Suppo de Souza [UNESP]
dc.contributor.authorLopes, Carlos Alberto de Magalhães
dc.contributor.institutionInstituto de Biociências Departamento de Microbiologia e Imunologia
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T15:09:25Z
dc.date.available2014-05-20T15:09:25Z
dc.date.issued2006-09-01
dc.description.abstractCoagulase-negative staphylococci (CNS) have been identified as the etiological agent in various infections and are currently the microorganisms most frequently isolated in nosocomial infections. However, little is known about the virulence factors produced by CNS that contribute to the pathogenesis of infections caused by these microorganisms. The study of CNS isolated from infectious processes of newborns hospitalized in the Neonatal Unit of the Hospital of the Botucatu Medical School, Unesp, indicated Staphylococcus epidermidis as the most frequently isolated species (77.8%), which was also associated with clinically significant situations. The analysis of virulence factors revealed the production of slime in 20 (17.1%) of all CNS samples isolated and the synthesis of a broad spectrum of enzymes and toxins, including hemolysins (19.6%), lipase (17.1%), lecithinase (3.4%), DNAse (15.4%), thermonuclease (7.7%), and enterotoxin A, B or C (37.6%). Taking into consideration that the etiological importance of CNS has often been neglected, the present investigation confirmed that these microorganisms should not be ignored or classified as mere contaminants.en
dc.description.affiliationInstituto de Biociências Departamento de Microbiologia e Imunologia
dc.description.affiliationUniversidade Estadual Paulista Faculdade de Medicina Departamento de Pediatria
dc.description.affiliationUnespUniversidade Estadual Paulista Faculdade de Medicina Departamento de Pediatria
dc.format.extent661-668
dc.identifierhttp://dx.doi.org/10.1590/S0074-02762006000600014
dc.identifier.citationMemórias do Instituto Oswaldo Cruz. Instituto Oswaldo Cruz, Ministério da Saúde, v. 101, n. 6, p. 661-668, 2006.
dc.identifier.doi10.1590/S0074-02762006000600014
dc.identifier.fileS0074-02762006000600014.pdf
dc.identifier.issn0074-0276
dc.identifier.lattes1197755531108177
dc.identifier.lattes0115647772315973
dc.identifier.scieloS0074-02762006000600014
dc.identifier.urihttp://hdl.handle.net/11449/27215
dc.language.isoeng
dc.publisherInstituto Oswaldo Cruz, Ministério da Saúde
dc.relation.ispartofMemórias do Instituto Oswaldo Cruz
dc.relation.ispartofjcr2.833
dc.relation.ispartofsjr1,172
dc.rights.accessRightsAcesso aberto
dc.sourceSciELO
dc.subjectcoagulase-negative staphylococcien
dc.subjectvirulence factorsen
dc.subjectslimeen
dc.subjectenzymesen
dc.subjecttoxinsen
dc.titleStudy of virulence factors in coagulase-negative staphylococci isolated from newbornsen
dc.typeArtigo
unesp.author.lattes1197755531108177
unesp.author.lattes0115647772315973
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt

Arquivos

Pacote Original
Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
S0074-02762006000600014.pdf
Tamanho:
612.87 KB
Formato:
Adobe Portable Document Format
Baixar
Licença do Pacote
Agora exibindo 1 - 2 de 2
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:

Coleções

Artigos - Pediatria - FMB