Morphometric study of the small intestinal mucosa in young, adult, and old rats submitted to protein deficiency and rehabilitation

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dc.contributor.authorRodrigues, Maria Aparecida Marchesan [UNESP]
dc.contributor.authorCamargo, João Lauro Viana de [UNESP]
dc.contributor.authorCoelho, Kunie Iabuki Rabello [UNESP]
dc.contributor.authorMontenegro, M. R.
dc.contributor.authorAngeleli, A. Y.
dc.contributor.authorBurini, Roberto Carlos [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T00:22:37Z
dc.date.available2014-05-27T00:22:37Z
dc.date.issued1985-10-16
dc.description.abstractLinear and stereological morphometric methods were applied to the jejunal and ileal mucosa of young, adult, and old male Wistar rats submitted to protein deficiency and rehabilitation. The animals were fed ad libitum a 2% casein diet during 42 days and then received a 20% casein diet for 30 days. Food intake, body weights, and plasma protein concentrations were recorded. In the young protein deficient rats values of mucosal height, surface area, and volume of the lamina propria were significantly lower than those of their age controls in both jejunum and ileum. In adults the differences were less marked and in the old rats all parameters were found to be unaltered by the protein deficient diet. The surface-to-volume ratio showed no significant differences between control and protein deficient in all three age groups, meaning that villus pattern did not change with protein deficiency. On rehabilitation, a striking difference between jejunum and ileum was observed in the young rats; all parameters returned to control levels in the jejunum, while they remained lower than those of their controls in the ileum.en
dc.format.extent816-821
dc.identifierhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC1432802/
dc.identifier.citationGut, v. 26, n. 8, p. 816-821, 1985.
dc.identifier.file2-s2.0-0021858896.pdf
dc.identifier.issn0017-5749
dc.identifier.lattes2287552780901172
dc.identifier.scopus2-s2.0-0021858896
dc.identifier.urihttp://hdl.handle.net/11449/63722
dc.language.isoeng
dc.relation.ispartofGut
dc.relation.ispartofjcr17.016
dc.relation.ispartofsjr7,440
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectanimal experiment
dc.subjectetiology
dc.subjecthistology
dc.subjectileum
dc.subjectjejunum
dc.subjectmorphometrics
dc.subjectnonhuman
dc.subjectpriority journal
dc.subjectprotein deficiency
dc.subjectrat
dc.subjectrehabilitation
dc.subjectsmall intestine
dc.subjectsmall intestine mucosa
dc.subjectAging
dc.subjectAnimals
dc.subjectBody Weight
dc.subjectIleum
dc.subjectIntestinal Mucosa
dc.subjectJejunum
dc.subjectMale
dc.subjectMicrovilli
dc.subjectProtein Deficiency
dc.subjectRats
dc.subjectRats, Inbred Strains
dc.titleMorphometric study of the small intestinal mucosa in young, adult, and old rats submitted to protein deficiency and rehabilitationen
dc.typeArtigo
unesp.author.lattes2287552780901172
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt

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