Atividade ectoparasiticida de uma nova formulação (benzoilfenilureia + organofosforado) em bovinos
Carregando...
Arquivos
Data
2018-10-01
Autores
Hardt, Isabela
Título da Revista
ISSN da Revista
Título de Volume
Editor
Universidade Estadual Paulista (Unesp)
Resumo
Os ectoparasitos de bovinos, sobretudo Rhipicephalus (Boophilus) microplus, Dermatobia hominis e Haematobia irritans constituem grande entrave à produtividade. O controle de tais ectoparasitos baseia-se, principalmente, no uso de quimioterápicos, cuja frequência e administração incorretas levaram ao surgimento de resistência a muitos princípios ativos. A pesquisa de novas alternativas quimioterápicas torna-se premente, razão pela qual, avaliou-se, neste trabalho, uma formulação inédita, contendo bezoilfenilureia + organofosforado. Os quatro estudos clínicos realizados possibilitaram avaliar a eficácia desta associação contra os três ectoparasitos supracitados. No carrapato, foram realizados dois estudos (infestação natural e artificial). O índice de eficácia anti-ixodídica em animais infestados naturalmente foi superior a 90% do 7º ao 28º DPT (Dia pós-tratamento). Nas infestações artificias foi utilizado o Fluazuron 2,5%, além da nova formulação (benzoilfenilureia + organofosforado), como parâmetro comparativo. O índice máximo de eficácia (100%) foi alcançado do 20º ao 47º DPT. Resultados semelhantes foram obtidos, pela formulação Fluazuron 2,5%. As eficácias terapêutica e residual da nova formulação contra Haematobia irritans (infestação natural) se manteve superior a 90% do 1º ao 14º DPT, alcançando índice mosquicida máximo (99,96%) no 1º DPT. Sobre larvas de Dermatobia hominis, a formulação inédita demonstrou efetividade superior a 90% do 7º ao 21º DPT. Em síntese, os resultados obtidos nos quatro estudos realizados, possibilitaram recomendar a referida formulação, inédita mundialmente, na dose e via empregadas, no tratamento e controle das principais ectoparasitoses de bovinos.
Cattle’s ectoparasites constitute a considerable productivity obstacle, especially Rhipicephalus (Boophilus) microplus, Dermatobia hominis and Haematobia irritans. The control of those ectoparasites is based mainly on the use of chemotherapeutics, whose frequency and incorrect administration have led to resistance of many active principles. The research of new chemotherapeutic alternatives became urgent, reason why, in this work, an unprecedented formulation containing benzoylphenyl urea + organophosphorade was evaluated. The four clinical studies made it possible to evaluated the efficacy of this combination against the three ectoparasites mentioned above. In the tick, two studies (natural and artificial infestations) were performed. The anti-ixodide efficacy index in naturally infested animals was greater than 90% from 7th to the 28th DPT (Post-Day Treatment). In the artificial infestations, Fluazuron 2.5% formulation was used as a comparative parameter to the new formulation (benzoylphenyl urea + organophosphate). The maximum efficacy index (100%) was reached from the 20th to the 47th DPT. Similar results were obtained by Fluazuron 2.5% formulation. The new formulation therapeutic and residual efficacies against Haematobia irritans (natural infestation) remained higher than 90% from the 1st DPT to the 14th DP, reaching a maximum index (99.96%) in the 1st DPT. Regarding larvae of Dermatobia hominis, the new formulation showed an effectiveness greater than 90% from the 7th to the 21st DPT. In summary, the results obtained in the four studies, made it possible to recommend this formulation, unprecedent worldwide, in the dose and via administrated, in the treatment and control of the main ectoparasitoses of cattle.
Cattle’s ectoparasites constitute a considerable productivity obstacle, especially Rhipicephalus (Boophilus) microplus, Dermatobia hominis and Haematobia irritans. The control of those ectoparasites is based mainly on the use of chemotherapeutics, whose frequency and incorrect administration have led to resistance of many active principles. The research of new chemotherapeutic alternatives became urgent, reason why, in this work, an unprecedented formulation containing benzoylphenyl urea + organophosphorade was evaluated. The four clinical studies made it possible to evaluated the efficacy of this combination against the three ectoparasites mentioned above. In the tick, two studies (natural and artificial infestations) were performed. The anti-ixodide efficacy index in naturally infested animals was greater than 90% from 7th to the 28th DPT (Post-Day Treatment). In the artificial infestations, Fluazuron 2.5% formulation was used as a comparative parameter to the new formulation (benzoylphenyl urea + organophosphate). The maximum efficacy index (100%) was reached from the 20th to the 47th DPT. Similar results were obtained by Fluazuron 2.5% formulation. The new formulation therapeutic and residual efficacies against Haematobia irritans (natural infestation) remained higher than 90% from the 1st DPT to the 14th DP, reaching a maximum index (99.96%) in the 1st DPT. Regarding larvae of Dermatobia hominis, the new formulation showed an effectiveness greater than 90% from the 7th to the 21st DPT. In summary, the results obtained in the four studies, made it possible to recommend this formulation, unprecedent worldwide, in the dose and via administrated, in the treatment and control of the main ectoparasitoses of cattle.
Descrição
Palavras-chave
Bovino, Parasito, Organofosforado, Ectoparasitos, Carrapato