Analysis of toxicity of ceramic nanoparticles and functional nanocomposites based on vulcanized natural rubber

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dc.contributor.authorBellucci, Felipe Silva [UNESP]
dc.contributor.authorFukushima, Jeferson Camargo [UNESP]
dc.contributor.authorDe Moraes, Josué
dc.contributor.authorNobre, Marcos Augusto Lima [UNESP]
dc.contributor.authorPaschoalini, Amarildo Tabone [UNESP]
dc.contributor.authorJob, Aldo Eloizo [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionCEP
dc.contributor.institutionResearch Center for Neglected Diseases - NPDN
dc.date.accessioned2018-12-11T17:28:48Z
dc.date.available2018-12-11T17:28:48Z
dc.date.issued2015-10-20
dc.description.abstractNanocomposites are multiphase materials of which, at least one of the phases, has a dimension smaller than 100 nm. These materials have attracted technological and scientific interest due to their multifunctional characteristics and potential, which allow them to combine unique properties which are not found in traditional commercial materials, such as natural rubber alone. The objective of this work is to analyse the toxicity of nanoparticles and nanocomposites when applied to mammal cells in order to obtain bioactive agents, as well as to evaluate the potential to be applied in biological systems. Ferroelectric ceramic nanoparticles of KSr2Nb5O15 (KSN) and paramagnetic ceramic nanoparticles Ni0.5Zn0.5Fe2O4 (NZF) were prepared and utilized to produce functional and multifunctional nanocomposites based on vulcanized natural rubber (NR/KSN and NR/NZF) with different nanoparticle concentrations. For both kinds of nanoparticles and both classes of nanocomposites, independently of the nanoparticle concentration, it is not possible to observe any reduction of the cellular viability until the incubation time is finished. In this way, these results point to the possibility of using these nanoparticles and nanocomposites, from the toxicity point of view, as bioactivity agents in biological systems based on mammalian cells.en
dc.description.affiliationSchool of Natural Sciences and Engineering - UNESP
dc.description.affiliationMinistry of Science Technology and Innovation - MCTI CEP
dc.description.affiliationResearch Center for Neglected Diseases - NPDN
dc.description.affiliationSchool of Technology and Applied Sciences - UNESP
dc.description.affiliationUnespSchool of Natural Sciences and Engineering - UNESP
dc.description.affiliationUnespSchool of Technology and Applied Sciences - UNESP
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipIdCAPES: 11208/13-9
dc.description.sponsorshipIdFAPESP: 2009/00523-8
dc.description.sponsorshipIdCNPq: 449999/2014-9
dc.description.sponsorshipIdCNPq: 454843/2014-3
dc.description.sponsorshipIdCNPq: 455323/2014-3
dc.description.sponsorshipIdCNPq: 480377/2013-8
dc.description.sponsorshipIdCAPES: BEX 5129/09-5
dc.identifierhttp://dx.doi.org/10.1051/matecconf/20152702004
dc.identifier.citationMATEC Web of Conferences, v. 27.
dc.identifier.doi10.1051/matecconf/20152702004
dc.identifier.file2-s2.0-84976358825.pdf
dc.identifier.issn2261-236X
dc.identifier.lattes7201928600704530
dc.identifier.scopus2-s2.0-84976358825
dc.identifier.urihttp://hdl.handle.net/11449/178111
dc.language.isoeng
dc.relation.ispartofMATEC Web of Conferences
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.titleAnalysis of toxicity of ceramic nanoparticles and functional nanocomposites based on vulcanized natural rubberen
dc.typeTrabalho apresentado em evento
unesp.author.lattes6475585105456744[6]
unesp.author.lattes8272223904033177[5]
unesp.author.lattes7201928600704530
unesp.author.orcid0000-0002-1979-8257[6]
unesp.author.orcid0000-0003-1887-2678[5]

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Artigos - Engenharia Mecânica - FEIS
Artigos - Física, Química e Biologia - FCT