Effects of glucose infusion on the endocrine, metabolic and cardiorespiratory responses to halothane anaesthesia of ponies

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dc.contributor.authorLuna, Stélio Pacca Loureiro [UNESP]
dc.contributor.authorTaylor, P. M.
dc.contributor.authorBrearley, J. C.
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversity of Cambridge
dc.contributor.institutionAnimal Health Trust
dc.date.accessioned2014-05-27T11:19:45Z
dc.date.available2014-05-27T11:19:45Z
dc.date.issued1999-07-24
dc.description.abstractGlucose was infused intravenously into six ponies during halothane anaesthesia, to evaluate its effect on their endocrine response to anaesthesia. The ponies were premedicated with acepromazine, and anaesthesia was induced with thiopentone and maintained with halothane in oxygen for two hours. Glucose was infused to maintain the plasma glucose concentration above 20 mmol/litre. Anaesthesia was associated with hypothermia, a decrease in haematocrit, hypotension, hyperoxaemia, respiratory acidosis and an increase in the plasma concentrations of lactate and arginine vasopressin. The concentration of β-endorphin in plasma increased transiently after 20 minutes but there were no changes in concentrations of adrenocorticotrophic hormone, dynorphin, cortisol or catecholamines. These data suggest that the glucose infusion attenuated the normal adrenal response of ponies to halothane anaesthesia.en
dc.description.affiliationDept. of Vet. Surg. and Anaesthiol. Fac. of Vet. Med. and Animal Science Unesp, Botucatu, São Paulo, 18618-000
dc.description.affiliationUniversity of Cambridge Dept. of Clin. Veterinary Medicine, Madingley Road, Cambridge CB3 0ES
dc.description.affiliationAnimal Health Trust, Newmarket CB8 7DW
dc.description.affiliationUnespDept. of Vet. Surg. and Anaesthiol. Fac. of Vet. Med. and Animal Science Unesp, Botucatu, São Paulo, 18618-000
dc.format.extent100-103
dc.identifierhttp://dx.doi.org/10.1136/vr.145.4.100
dc.identifier.citationVeterinary Record, v. 145, n. 4, p. 100-103, 1999.
dc.identifier.doi10.1136/vr.145.4.100
dc.identifier.issn0042-4900
dc.identifier.lattes4473260410099623
dc.identifier.orcid0000-0001-5312-9076
dc.identifier.scopus2-s2.0-0033600471
dc.identifier.urihttp://hdl.handle.net/11449/65810
dc.identifier.wosWOS:000082051400008
dc.language.isoeng
dc.relation.ispartofVeterinary Record
dc.relation.ispartofjcr2.050
dc.relation.ispartofsjr0,464
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectacepromazine
dc.subjectargipressin
dc.subjectbeta endorphin
dc.subjectcatecholamine
dc.subjectcorticotropin
dc.subjectdynorphin
dc.subjecthalothane
dc.subjecthydrocortisone
dc.subjectinhalation anesthetic agent
dc.subjectlactic acid
dc.subjectthiopental
dc.subjectanesthesia induction
dc.subjectanimal experiment
dc.subjectanimal model
dc.subjectbreathing
dc.subjectcardiovascular response
dc.subjectcatecholamine blood level
dc.subjectcontrolled study
dc.subjectcorticotropin blood level
dc.subjectglucose blood level
dc.subjectglucose infusion
dc.subjecthematocrit
dc.subjecthormone release
dc.subjecthorse
dc.subjecthydrocortisone blood level
dc.subjecthypotension
dc.subjecthypothermia
dc.subjectinhalation anesthesia
dc.subjectinhalational drug administration
dc.subjectintravenous drug administration
dc.subjectlactate blood level
dc.subjectmale
dc.subjectmetabolism
dc.subjectnonhuman
dc.subjectpremedication
dc.subjectrespiratory acidosis
dc.subjectAdrenal Glands
dc.subjectAnesthetics, Inhalation
dc.subjectAnimals
dc.subjectEndocrine System
dc.subjectGlucose
dc.subjectHalothane
dc.subjectHeart Rate
dc.subjectHorses
dc.subjectMale
dc.subjectRespiration
dc.subjectAnimalia
dc.subjectEquus caballus
dc.titleEffects of glucose infusion on the endocrine, metabolic and cardiorespiratory responses to halothane anaesthesia of poniesen
dc.typeArtigo
dcterms.licensehttp://www.bmj.com/about-bmj/resources-authors
unesp.author.lattes4473260410099623
unesp.author.orcid0000-0001-5312-9076[1]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina Veterinária e Zootecnia, Botucatupt

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