Evaluation of tissue reaction to Aroeira (Myracrodruon urundeuva) extracts: a histologic and edemogenic study

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dc.contributor.authorMachado, Alessandra Cury [UNESP]
dc.contributor.authorDezan Júnior, Eloi [UNESP]
dc.contributor.authorEduardo Gomes-Filho, Joao [UNESP]
dc.contributor.authorCintra, Luciano Tavares Angelo [UNESP]
dc.contributor.authorRuviere, Denise Belucio [UNESP]
dc.contributor.authorZoccal, Renata [UNESP]
dc.contributor.authorDamante, Carla Andreotti [UNESP]
dc.contributor.authorJardim Júnior, Élerson Gaetti [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.date.accessioned2013-09-30T18:30:31Z
dc.date.accessioned2014-05-20T13:44:11Z
dc.date.available2013-09-30T18:30:31Z
dc.date.available2014-05-20T13:44:11Z
dc.date.issued2012-07-01
dc.description.abstractObjectives: This study evaluated subcutaneous tissue response to Aroeira (Myracrodruon urundeuva) extract employing edemogenic and histological analyses. Material and methods: Test groups consisted of aqueous and ethanolic Aroeira extracts and saline (control). For groups consisted of aqueous and ethanolic Aroeira extracts and saline Blue. After 30 min, the extracts and saline were injected on the dorsum of the rats, which were then sacrificed after 3 and 6 h. Readings were performed in a spectrophotometer. For subcutaneous implantation, 30 rats received a polyethylene tube containing the extracts on their dorsum and then they were killed after 7 and 28 days. The samples were processed for histological analysis and evaluated with a light microscope. The inflammatory infiltrate was quantified. Results: There were no statistically significant differences between aqueous extract and saline groups in relation to edema quantification in the different periods (p > 0.05). Ethanolic solution resulted in more edema independently of the experimental period (p < 0.05). Histological analysis showed similar results on the 7-day period for the 3 groups. There was a notable reduction on inflammatory cell number for saline and aqueous extract groups at 28 days. Conclusion: The aqueous extract showed biocompatible properties similar to those of saline.en
dc.description.affiliationUNESP Univ Estadual Paulista, Aracatuba Sch Dent, Dept Pediat, Aracatuba, SP, Brazil
dc.description.affiliationUNESP Univ Estadual Paulista, Aracatuba Sch Dent, Dept Endodont, Aracatuba, SP, Brazil
dc.description.affiliationUNESP Univ Estadual Paulista, Aracatuba Sch Dent, Dept Microbiol, Aracatuba, SP, Brazil
dc.description.affiliationUniv São Paulo, Bauru Sch Dent, Dept Periodontol, Bauru, SP, Brazil
dc.description.affiliationUnespUNESP Univ Estadual Paulista, Aracatuba Sch Dent, Dept Pediat, Aracatuba, SP, Brazil
dc.description.affiliationUnespUNESP Univ Estadual Paulista, Aracatuba Sch Dent, Dept Endodont, Aracatuba, SP, Brazil
dc.description.affiliationUnespUNESP Univ Estadual Paulista, Aracatuba Sch Dent, Dept Microbiol, Aracatuba, SP, Brazil
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.format.extent414-418
dc.identifierhttp://dx.doi.org/10.1590/S1678-77572012000400005
dc.identifier.citationJournal of Applied Oral Science. Bauru-sp: Univ São Paulo Fac Odontologia Bauru, v. 20, n. 4, p. 414-418, 2012.
dc.identifier.fileS1678-77572012000400005.pdf
dc.identifier.issn1678-7757
dc.identifier.lattes8813777272581972
dc.identifier.lattes9235743081667362
dc.identifier.lattes4605992512582464
dc.identifier.scieloS1678-77572012000400005
dc.identifier.urihttp://hdl.handle.net/11449/15472
dc.identifier.wosWOS:000309419000005
dc.language.isoeng
dc.publisherUniversidade de São Paulo (USP), Faculdade de Odontologia de Bauru
dc.relation.ispartofJournal of Applied Oral Science
dc.relation.ispartofjcr1.709
dc.relation.ispartofsjr0,645
dc.rights.accessRightsAcesso aberto
dc.sourceWeb of Science
dc.subjectInflammationen
dc.subjectEdemaen
dc.subjectMedicinal plantsen
dc.subjectAnacardiaceaeen
dc.titleEvaluation of tissue reaction to Aroeira (Myracrodruon urundeuva) extracts: a histologic and edemogenic studyen
dc.typeArtigo
dcterms.licensehttp://www.scielo.br/revistas/jaos/paboutj.htm
dcterms.rightsHolderUniv São Paulo Fac Odontologia Bauru
unesp.author.lattes8813777272581972
unesp.author.lattes9235743081667362
unesp.author.lattes4605992512582464
unesp.author.orcid0000-0003-2348-7846[4]
unesp.author.orcid0000-0002-5699-6578[2]
unesp.author.orcid0000-0001-5994-2287[3]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Odontologia, Araçatubapt

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Artigos - Patologia e Propedêutica Clínica - FOA