Ausência de arteriosclerose na porção intramiocárdica das artérias coronárias: Um mistério a ser resolvido?

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dc.contributor.authorRamalli Jr, Edvaldo Luiz
dc.contributor.authorBraga, Leonardo Henrique
dc.contributor.authorEvora, Patricia Martinez [UNESP]
dc.contributor.authorAlbuquerque, Agnes Afrodite Sumarelli
dc.contributor.authorCelotto, Andrea Carla
dc.contributor.authorMota, André Lupp
dc.contributor.authorEvora, Paulo Roberto Barbosa
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionLaboratory of Vascular Reactivity and Endothelial Function
dc.contributor.institutionLaboratory of Biomedical Vascular Reactivity and Endothelial Function
dc.contributor.institutionUniversidade de São
dc.date.accessioned2014-05-27T11:25:56Z
dc.date.available2014-05-27T11:25:56Z
dc.date.issued2011-07-01
dc.description.abstractSeveral studies show that portions of intramyocardial coronary arteries are spared of arteriosclerosis, involving morphological, embryological, biochemical and pathophysiological aspects. Endothelial function is significantly affected in the segment of transition, as estimated by the vasoactive response to Ach. These findings suggest that myocardial bridge can provide protection against arteriosclerosis by counteracting the negative effects of endothelial dysfunction. The intramyocardial portion's protection phenomenon deserves further scientific research on all research fronts. Improved morphological, biomechanical and especially physiological and embryological knowledge may be the key to a future window of opportunity for chronic arterial disease therapy and prevention. In addition, this review discusses possible therapeutic approaches for symptomatic coronary ischemia caused by myocardial bridges.en
dc.description.affiliationMonitor, Surgery and Anatomy Department Faculdade de Medicina de Ribeirão Preto Universidade de São Paulo, Ribeirão Preto, SP
dc.description.affiliationGraduate School of Veterinary Sciences of Jaboticabal UNESP, Jaboticabal, SP
dc.description.affiliationLaboratory of Vascular Reactivity and Endothelial Function, Ribeirão Preto, SP
dc.description.affiliationLaboratory of Biomedical Vascular Reactivity and Endothelial Function, Ribeirão Preto, SP
dc.description.affiliationResident of Surgery and Anatomy Department Faculdade de Medicina de Ribeirão Preto Universidade de São, Paulo, Ribeirão Preto, SP
dc.description.affiliationDepartment Chief of Faculdade de Medicina de Ribeirão Preto Universidade de São Paulo, Ribeirão Preto, SP
dc.description.affiliationUnespGraduate School of Veterinary Sciences of Jaboticabal UNESP, Jaboticabal, SP
dc.format.extent440-446
dc.identifierhttp://dx.doi.org/10.5935/1678-9741.20110020
dc.identifier.citationBrazilian Journal of Cardiovascular Surgery, v. 26, n. 3, p. 440-446, 2011.
dc.identifier.doi10.5935/1678-9741.20110020
dc.identifier.file2-s2.0-81355133336.pdf
dc.identifier.issn0102-7638
dc.identifier.issn1678-9741
dc.identifier.scopus2-s2.0-81355133336
dc.identifier.urihttp://hdl.handle.net/11449/72538
dc.language.isoeng
dc.language.isopor
dc.relation.ispartofBrazilian Journal of Cardiovascular Surgery
dc.relation.ispartofjcr0.805
dc.relation.ispartofsjr0,231
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectCoronary circulation
dc.subjectEndothelium
dc.subjectMyocardial bridging
dc.subjectACE protein, human
dc.subjectdipeptidyl carboxypeptidase
dc.subjectendothelin 1
dc.subjectadipose tissue
dc.subjectcoronary artery blood flow
dc.subjectcoronary artery disease
dc.subjectcoronary blood vessel
dc.subjecthistology
dc.subjecthuman
dc.subjectmetabolism
dc.subjectmyocardial bridging
dc.subjectparacrine signaling
dc.subjectpathology
dc.subjectpathophysiology
dc.subjectphysiology
dc.subjectprenatal development
dc.subjectreview
dc.subjectvascular endothelium
dc.subjectAdipose Tissue
dc.subjectCoronary Artery Disease
dc.subjectCoronary Circulation
dc.subjectCoronary Vessels
dc.subjectEndothelin-1
dc.subjectEndothelium, Vascular
dc.subjectHumans
dc.subjectMyocardial Bridging
dc.subjectParacrine Communication
dc.subjectPeptidyl-Dipeptidase A
dc.titleAusência de arteriosclerose na porção intramiocárdica das artérias coronárias: Um mistério a ser resolvido?pt
dc.title.alternativeAbsence of arteriosclerosis in intramyocardial coronary arteries: A mystery to be solved?en
dc.typeArtigo
dcterms.licensehttp://www.scielo.br/revistas/rbccv/iaboutj.htm

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