Lymphoepithelioma-like carcinoma of the skin

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dc.contributor.authorOliveira, Cristiano Claudino [UNESP]
dc.contributor.authorMarques, Mariângela Esther Alencar [UNESP]
dc.contributor.authorNóbrega, Vinicius Cardoso [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2018-12-11T17:19:51Z
dc.date.available2018-12-11T17:19:51Z
dc.date.issued2018-03-01
dc.description.abstractPrimary cutaneous lymphoepithelioma-like carcinoma is a rare disease with low metastatic potential. Its morphologic and pathological features are similar to those of nasopharyngeal lymphoepithelial carcinoma. We report the case of a 60-year-old man with an infrapalpebral pearly papule, measuring 0.6 cm in diameter. The lesion was excised with a clinical hypothesis of basal cell carcinoma or squamous cell carcinoma. Histopathological analysis revealed a malignant neoplasm with syncytial arrangement of cells with vesicular nuclei, associated with dense lymphocytic infiltrate. Immunohistochemistry revealed cytokeratin-positive cells (AE1/AE3) and p63 protein, indicating epithelial histogenesis and squamous differentiation. A negative Epstein-Barr virus test result was achieved by immunohistochemistry. Primary lymphoepithelioma-like carcinoma of the skin is a differential diagnosis of lesions with prominent inflammatory infiltrates.en
dc.description.affiliationDepartment of Pathology of the Botucatu School of Medicine Universidade Estadual Paulista “Júlio de Mesquita Filho” (FMB-UNESP)
dc.description.affiliationUnespDepartment of Pathology of the Botucatu School of Medicine Universidade Estadual Paulista “Júlio de Mesquita Filho” (FMB-UNESP)
dc.format.extent256-258
dc.identifierhttp://dx.doi.org/10.1590/abd1806-4841.20187205
dc.identifier.citationAnais Brasileiros de Dermatologia, v. 93, n. 2, p. 256-258, 2018.
dc.identifier.doi10.1590/abd1806-4841.20187205
dc.identifier.fileS0365-05962018000200256.pdf
dc.identifier.issn1806-4841
dc.identifier.issn0365-0596
dc.identifier.lattes7528116925519142
dc.identifier.scieloS0365-05962018000200256
dc.identifier.scopus2-s2.0-85046427410
dc.identifier.urihttp://hdl.handle.net/11449/176263
dc.language.isoeng
dc.relation.ispartofAnais Brasileiros de Dermatologia
dc.relation.ispartofsjr0,520
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectImmunohistochemistry
dc.subjectPathology
dc.subjectSkin neoplasms
dc.titleLymphoepithelioma-like carcinoma of the skinen
dc.typeArtigo
unesp.author.lattes7528116925519142

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