Association between solitary keratoacanthoma and cigarette smoking: A case-control study

dc.contributor.authorMiot, Hélio Amante [UNESP]
dc.contributor.authorMiot, Luciane Donida Bartoli [UNESP]
dc.contributor.authorCosta, Ana Laura Bastos da [UNESP]
dc.contributor.authorMatsuo, Cristiane Yuri [UNESP]
dc.contributor.authorStolf, Hamilton Ometto [UNESP]
dc.contributor.authorMarques, Mariângela Esther Alencar [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:22:04Z
dc.date.available2014-05-27T11:22:04Z
dc.date.issued2006-12-01
dc.description.abstractSolitary keratoacanthoma (KA) is a common benign epithelial tumor of the skin characterized by rapid growth and a tendency toward spontaneous regression. The exact etiology and classification of KA are a matter of debate. Smokers also seem to be more affected than persons who never smoke. The objective of this study was to evaluate the association between solitary KA and smoking habit. A case-control study involving 78 patients diagnosed with KA and 199 controls from the related community was performed to evaluate the association between cigarette smoking and KA. A higher smoking prevalence was noted in cases (69.2 %) than controls (21.6 %) and the odds ratio adjusted for sex and age was 9.1 (95 % CI 4.9 to 17.1, p< 0.01). The mean tumoral diameter at surgery and the site of involvement was not statistically related to smoking. These findings suggest that cigarette smoking is associated with the development of KA. © 2006 Dermatology Online Journal.en
dc.description.affiliationDermatology Department Unesp Medical School, Botucatu SP
dc.description.affiliationUnesp Medical School, Botucatu - SP
dc.description.affiliationPathology Department Unesp Medical School, Botucatu - SP
dc.description.affiliationUnespDermatology Department Unesp Medical School, Botucatu SP
dc.description.affiliationUnespUnesp Medical School, Botucatu - SP
dc.description.affiliationUnespPathology Department Unesp Medical School, Botucatu - SP
dc.identifierhttp://escholarship.org/uc/item/2wt2t8hm
dc.identifier.citationDermatology Online Journal, v. 12, n. 2, 2006.
dc.identifier.issn1087-2108
dc.identifier.lattes2543633050941005
dc.identifier.lattes1885384405893048
dc.identifier.lattes7528116925519142
dc.identifier.scopus2-s2.0-33846504883
dc.identifier.urihttp://hdl.handle.net/11449/69316
dc.language.isoeng
dc.relation.ispartofDermatology Online Journal
dc.relation.ispartofsjr0,327
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectadult
dc.subjectcigarette smoking
dc.subjectcontrolled study
dc.subjectepithelium tumor
dc.subjecthuman
dc.subjectkeratoacanthoma
dc.subjectmajor clinical study
dc.subjectprevalence
dc.subjectrisk factor
dc.subjectskin cancer
dc.subjectsmoking habit
dc.subjecttumor volume
dc.titleAssociation between solitary keratoacanthoma and cigarette smoking: A case-control studyen
dc.typeArtigo
unesp.author.lattes2543633050941005
unesp.author.lattes1885384405893048
unesp.author.lattes7528116925519142
unesp.author.orcid0000-0001-6947-5627[6]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt

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