Influence of bioadhesive polymers on the protective effect of fluoride against erosion

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dc.contributor.authorÁvila, Daniele Mara da Silva [UNESP]
dc.contributor.authorZanatta, Rayssa Ferreira [UNESP]
dc.contributor.authorScaramucci, Tais
dc.contributor.authorAoki, Idalina Vieira
dc.contributor.authorTorres, Carlos Rocha Gomes [UNESP]
dc.contributor.authorBorges, Alessandra Bühler [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.date.accessioned2018-12-11T17:30:34Z
dc.date.available2018-12-11T17:30:34Z
dc.date.issued2017-01-01
dc.description.abstractObjective This study investigated if the incorporation of the bioadhesive polymers Carbopol 980, Carboxymethyl cellulose (CMC), and Aristoflex AVC in a fluoridated solution (NaF–900 ppm) would increase the solution's protective effect against enamel erosion. Methods Enamel specimens were submitted to a 5-day de-remineralization cycling model, consisting of 2 min immersions in 0.3% citric acid (6x/day), 1 min treatments with the polymers (associated or not with fluoride), and 60 min storage in artificial saliva. Ultrapure water was used as the negative control and a 900 ppm fluoride solution as positive control. The initial Knoop microhardness (KHN1) was used to randomize the samples into groups. Another two microhardness assessments were performed after the first (KHN2) and second (KHN3) acid immersions, to determine initial erosion in the first day. The formula: %KHNalt = [(KHN3-KHN2)/KHN2]*100 was used to define the protective effect of the treatments. After the 5-day cycling, surface loss (SL, in μm) was evaluated with profilometry. Data were analyzed with 2-way ANOVA and Tukey's tests (p < 0.05). Results For %KHNalt, the polymers alone did not reduce enamel demineralization when compared to the negative control, but Carbopol associated with NaF significantly improved its protective effect. The profilometric analysis showed that Carbopol, associated or not with NaF, exhibited the lowest SL, while CMC and Aristoflex did not exhibit a protective effect, nor were they able to improve the protection of NaF. Conclusions It is concluded that Carbopol enhanced NaF's protection against initial erosion. Carbopol alone or associated with NaF was able to reduce SL after several erosive challenges. Clinical significance Carbopol by itself was able to reduce the erosive wear magnitude to the same extent as the sodium fluoride, therefore, is a promising agent to prevent or control enamel erosion.en
dc.description.affiliationDepartment of Restorative Dentistry Institute of Science and Technology São Paulo State University-UNESP
dc.description.affiliationDepartment of Restorative Dentistry São Paulo University-USP
dc.description.affiliationDepartment of Chemical Engineering Polytechnic School São Paulo University-USP
dc.description.affiliationUnespDepartment of Restorative Dentistry Institute of Science and Technology São Paulo State University-UNESP
dc.format.extent45-52
dc.identifierhttp://dx.doi.org/10.1016/j.jdent.2016.10.015
dc.identifier.citationJournal of Dentistry, v. 56, p. 45-52.
dc.identifier.doi10.1016/j.jdent.2016.10.015
dc.identifier.file2-s2.0-85006074073.pdf
dc.identifier.issn0300-5712
dc.identifier.scopus2-s2.0-85006074073
dc.identifier.urihttp://hdl.handle.net/11449/178477
dc.language.isoeng
dc.relation.ispartofJournal of Dentistry
dc.relation.ispartofsjr1,919
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectDental erosion
dc.subjectEnamel
dc.subjectFluoride
dc.subjectMicrohardness
dc.subjectPolymers
dc.subjectProfilometry
dc.titleInfluence of bioadhesive polymers on the protective effect of fluoride against erosionen
dc.typeArtigo
unesp.author.lattes6960470053037905[6]
unesp.author.lattes3135367849609938[5]
unesp.author.orcid0000-0001-7686-089X[6]
unesp.author.orcid0000-0002-9485-5514[5]

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Artigos - Odontologia Restauradora - ICT