Metabolic Effects of the Ingestion of Different Fructose Sources in Rats

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dc.contributor.authorMeirelles, C. J. C. S.
dc.contributor.authorOliveira, L. A. [UNESP]
dc.contributor.authorJordao, A. A.
dc.contributor.authorNavarro, A. M.
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T13:23:39Z
dc.date.available2014-05-20T13:23:39Z
dc.date.issued2011-04-01
dc.description.abstractIntroduction: Fructose is a simple carbohydrate that should be ingested in a restricted manner. However, current data suggest increased daily consumption of fructose which may lead to an increased incidence of diseases such as obesity, diabetes and co-morbidities associated with excess weight. Thus, the objective of the present study was to assess the effect of the ingestion of different fructose sources on weight gain, glycemia and serum triglyceride levels in rats.Methods: The study was conducted on male Wistar rats divided into 5 groups according to the source and concentration of fructuse (ingested ad libitum in liquid form).Results: Drink intake was increased and chow consumption was reduced in all groups compared to control (p<0.05). The animals of the groups receiving 10 and 20% fructose solutions showed increased triglyceride levels and the 20% group also showed weight gain. The exaggerate consumption of fructose promotes a reduced consumption of chow, an increase in serum triglyceride levels, and weight gain in some animals.en
dc.description.affiliationUSP, Fac Med Ribeirao Preto, Dept Med, BR-14049900 Ribeirao Preto, SP, Brazil
dc.description.affiliationUNESP, Dept Foods, Fac Pharmaceut Sci Araraquara, Jaboticabal, SP, Brazil
dc.description.affiliationUnespUNESP, Dept Foods, Fac Pharmaceut Sci Araraquara, Jaboticabal, SP, Brazil
dc.format.extent218-220
dc.identifierhttp://dx.doi.org/10.1055/s-0031-1275276
dc.identifier.citationExperimental and Clinical Endocrinology & Diabetes. Stuttgart: Johann Ambrosius Barth Verlag Medizinverlage Heidelberg Gmbh, v. 119, n. 4, p. 218-220, 2011.
dc.identifier.doi10.1055/s-0031-1275276
dc.identifier.issn0947-7349
dc.identifier.urihttp://hdl.handle.net/11449/7167
dc.identifier.wosWOS:000290740800005
dc.language.isoeng
dc.publisherJohann Ambrosius Barth Verlag Medizinverlage Heidelberg Gmbh
dc.relation.ispartofExperimental and Clinical Endocrinology & Diabetes
dc.relation.ispartofjcr1.623
dc.relation.ispartofsjr0,695
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectfructoseen
dc.subjectglycemiaen
dc.subjectweight gainen
dc.subjecttriglyceridesen
dc.titleMetabolic Effects of the Ingestion of Different Fructose Sources in Ratsen
dc.typeArtigo
dcterms.licensehttp://www.thieme.de/fz/_pdf/thieme_ir_policy_english.pdf
dcterms.rightsHolderJohann Ambrosius Barth Verlag Medizinverlage Heidelberg Gmbh
unesp.author.orcid0000-0001-9127-3001[4]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Ciências Farmacêuticas, Araraquarapt

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Artigos - Alimentos e Nutrição - FCFAR