Serum protein profile of Holstein cows during the transition period

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dc.contributor.authorReis, J. F.
dc.contributor.authorMadureira, K. M.
dc.contributor.authorSilva, C. P. C.
dc.contributor.authorBaldacim, V. P. A.
dc.contributor.authorFagliari, J. J. [UNESP]
dc.contributor.authorGomes, V.
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Federal da Bahia (UFBA)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2018-11-27T16:55:49Z
dc.date.available2018-11-27T16:55:49Z
dc.date.issued2016-05-01
dc.description.abstractThe aim of this study was to evaluate longitudinally the serum protein profile of 13 Holstein cows during the transition period. Blood samples (n=78) were taken weekly, from the second week before parturition (M-2) to the third week after parturition (M3) for determination of serum protein profile by biochemical tests (total serum protein - PT) and SDS-PAGE electrophoresis, for the other proteins analyzed. PT values decreased gradually (P = 0.000) from M-2 (6.4g/dL) to M0 (6.2g/dL), increasing in subsequent moments (M3 = 7.3g/dL). The concentrations of the heavy chain (M-2=919.4; M-1=1074.5mg/dL) and the light chain of IgG (M-2=393.9; M-1=466.7mg/dL) were lower in pre-calving compared to post calving (M1=1,283.3; M2=1,374.2 and M3=1,630.3 mg/dL for the heavy chain, and M1=463.4; M2=573.7 and M3=651,8 mg/dL for the light chain of IgG). For IgA there was a decrease in the values (P=0.001), from M-2 (51.9mg/dL) to M1 (34.0mg/dL), and increase in M2 (45,4g/dL) and M3 (62,6g/dL). The values of haptoglobin (Hp) and ceruloplasmin (Cp) increased (P=0,000) from M-2 (Hp=16.6mg/dL; Cp=8.6 mg/dL) to M3 (Hp=60.9mg/dL; Cp=127.1mg/dl). Albumin showed slight variations during the transition period (P=0.000), while the serum transferrin (P=0.101) and acid glycoprotein (P=0.105) were stable. Body condition score (BCS) was also analyzed during the transition period, checking the difference (P=0.003) between M-2 (ECC=4.0) and M1 (ECC=3.0). It was also reported the occurrence of dystocia (4/13), retained placenta (1/13) and hypocalcemia (1/13) on the day of calving (M0) and uterine infections (5/13) and ketosis (1/13) occurring in the post calving. In conclusion, there was an increase in serum Hp and Cp, and a decrease in the immunoglobulins and transferrin amounts in Holstein cows during the transition period, related to diseases occurring during this period and the high BCS, promoting metabolic changes and immunosuppression.en
dc.description.affiliationUniv Sao Paulo, Fac Med Vet & Zootecnia, Sao Paulo, SP, Brazil
dc.description.affiliationUniv Fed Bahia, Escola Med Vet & Zootecnia, Salvador, BA, Brazil
dc.description.affiliationUniv Estadual Paulista, Fac Ciencias Agr & Vet, Jaboticabal, SP, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Fac Ciencias Agr & Vet, Jaboticabal, SP, Brazil
dc.format.extent587-595
dc.identifierhttp://dx.doi.org/10.1590/1678-4162-8772
dc.identifier.citationArquivo Brasileiro De Medicina Veterinaria E Zootecnia. Minas Gerais: Arquivo Brasileiro Medicina Veterinaria Zootecnia, v. 68, n. 3, p. 587-595, 2016.
dc.identifier.doi10.1590/1678-4162-8772
dc.identifier.fileS0102-09352016000300587.pdf
dc.identifier.issn0102-0935
dc.identifier.scieloS0102-09352016000300587
dc.identifier.urihttp://hdl.handle.net/11449/165227
dc.identifier.wosWOS:000379354600005
dc.language.isopor
dc.publisherArquivo Brasileiro Medicina Veterinaria Zootecnia
dc.relation.ispartofArquivo Brasileiro De Medicina Veterinaria E Zootecnia
dc.relation.ispartofsjr0,248
dc.rights.accessRightsAcesso aberto
dc.sourceWeb of Science
dc.subjectinflammation
dc.subjectproteins
dc.subjectperipartum
dc.subjectbovine
dc.titleSerum protein profile of Holstein cows during the transition perioden
dc.typeArtigo
dcterms.rightsHolderArquivo Brasileiro Medicina Veterinaria Zootecnia

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