Syndromic craniosynostosis: neuropsycholinguistic abilities and imaging analysis of the central nervous system

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dc.contributor.authorMaximino, Luciana Paula
dc.contributor.authorDucati, Luis Gustavo [UNESP]
dc.contributor.authorMarques Abramides, Dagma Venturini
dc.contributor.authorCorrea, Camila de Castro [UNESP]
dc.contributor.authorGarcia, Patricia Fernandes
dc.contributor.authorFernandes, Adriano Yacubian [UNESP]
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2018-11-26T17:42:45Z
dc.date.available2018-11-26T17:42:45Z
dc.date.issued2017-12-01
dc.description.abstractObjective: To characterize patients with syndromic craniosynostosis with respect to their neuropsycholinguistic abilities and to present these findings together with the brain abnormalities. Methods: Eighteen patients with a diagnosis of syndromic craniosynostosis were studied. Eight patients had Apert syndrome and 10 had Crouzon syndrome. They were submitted to phonological evaluation, neuropsychological evaluation and magnetic resonance imaging of the brain. The phonological evaluation was done by behavioral observation of the language, the Peabody test, Token test and a school achievement test. The neuropsychological evaluation included the WISC III and WAIS tests. Results: Abnormalities in language abilities were observed and the school achievement test showed abnormalities in 66.67% of the patients. A normal intelligence quotient was observed in 39.3% of the patients, and congenital abnormalities of the central nervous system were observed in 46.4% of the patients. Conclusion: Abnormalities of language abilities were observed in the majority of patients with syndromic craniosynostosis, and low cognitive performance was also observed.en
dc.description.affiliationUniv Sao Paulo, Fac Odontol Bauru, Dept Fonoaudiol & Audiol, Bauru, SP, Brazil
dc.description.affiliationUniv Sao Paulo, Hosp Reabil Anomalias Craniofaciais, Bauru, SP, Brazil
dc.description.affiliationUniv Estadual Paulista, Fac Med Botucatu, Dept Oftalmot Otorrinilaringol & Cirurgia Cabeca, Botucatu, SP, Brazil
dc.description.affiliationUniv Estadual Paulista, Fac Med Botucatu, Dept Neurol Psicol & Psiquiat, Botucatu, SP, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Fac Med Botucatu, Dept Oftalmot Otorrinilaringol & Cirurgia Cabeca, Botucatu, SP, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Fac Med Botucatu, Dept Neurol Psicol & Psiquiat, Botucatu, SP, Brazil
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipIdFAPESP: 2000/080803
dc.description.sponsorshipIdCNPq: 307043/2008-8
dc.format.extent862-868
dc.identifierhttp://dx.doi.org/10.1590/0004-282X20170171
dc.identifier.citationArquivos De Neuro-psiquiatria. Sao Paulo Sp: Assoc Arquivos Neuro- Psiquiatria, v. 75, n. 12, p. 862-868, 2017.
dc.identifier.doi10.1590/0004-282X20170171
dc.identifier.fileS0004-282X2017001200862.pdf
dc.identifier.issn0004-282X
dc.identifier.lattes8645742570984986
dc.identifier.orcid0000-0002-2915-1852
dc.identifier.scieloS0004-282X2017001200862
dc.identifier.urihttp://hdl.handle.net/11449/163615
dc.identifier.wosWOS:000417621200005
dc.language.isoeng
dc.publisherAssoc Arquivos Neuro- Psiquiatria
dc.relation.ispartofArquivos De Neuro-psiquiatria
dc.rights.accessRightsAcesso aberto
dc.sourceWeb of Science
dc.subjectacrocephalosyndactylia
dc.subjectcraniofacial dysostosis
dc.subjectcentral nervous system
dc.subjectneuropsychology
dc.subjectlanguage
dc.titleSyndromic craniosynostosis: neuropsycholinguistic abilities and imaging analysis of the central nervous systemen
dc.typeArtigo
dcterms.rightsHolderAssoc Arquivos Neuro- Psiquiatria
unesp.author.lattes8645742570984986[6]
unesp.author.orcid0000-0002-2915-1852[6]

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