A systematic review of anti-inflammatories for mild to moderate carpal tunnel syndrome

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dc.contributor.authorFilho, Pedro Tadao Hamamoto [UNESP]
dc.contributor.authorLeite, Fabio Vicente [UNESP]
dc.contributor.authorRuiz, Tânia [UNESP]
dc.contributor.authorResende, Luiz Antonio de Lima [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:23:57Z
dc.date.available2014-05-27T11:23:57Z
dc.date.issued2009-09-01
dc.description.abstractThe purpose of this study was to evaluate anti-inflammatory drugs in the medium- and long-term management of mild to moderate carpal tunnel syndrome (CTS). The authors conducted a systematic review of the literature on the effectiveness of steroidal and nonsteroidal anti-inflammatory drugs for mild and moderate cases of CTS. There were included only randomized, double-blind clinical trials. Six publications referring to five trials were included in the review. No study on nonsteroidal anti-inflammatory drugs met our inclusion criteria. Although neurophysiological studies have not shown great differences resulting from the application of corticosteroids, the symptomatic benefit provided by such drugs is clear. In the short term, local infiltration provides better results than systemic administration of corticosteroids. Over a 1-year period, however, this difference does not persist. Further double-blind randomized trials evaluating therapeutic efficacy for a longer follow-up period are required to provide stronger evidence for both steroidal and nonsteroidal anti-inflammatories. © 2009 by Lippincott Williams & Wilkins.en
dc.description.affiliationBotucatu Medical School São Paulo State University, São Paulo
dc.description.affiliationDepartment of Public Health Botucatu Medical School São Paulo State University, São Paulo
dc.description.affiliationDepartment of Neurology, Psychology and Psychiatry Botucatu Medical School São Paulo State University, São Paulo
dc.description.affiliationFaculdade de Medicina de Botucatu UNESP, Distrito de Rubião Jr, s/, n Botucatu/SP, 18.618-970
dc.description.affiliationUnespBotucatu Medical School São Paulo State University, São Paulo
dc.description.affiliationUnespDepartment of Public Health Botucatu Medical School São Paulo State University, São Paulo
dc.description.affiliationUnespDepartment of Neurology, Psychology and Psychiatry Botucatu Medical School São Paulo State University, São Paulo
dc.description.affiliationUnespFaculdade de Medicina de Botucatu UNESP, Distrito de Rubião Jr, s/, n Botucatu/SP, 18.618-970
dc.format.extent22-30
dc.identifierhttp://dx.doi.org/10.1097/CND.0b013e3181ac8364
dc.identifier.citationJournal of Clinical Neuromuscular Disease, v. 11, n. 1, p. 22-30, 2009.
dc.identifier.doi10.1097/CND.0b013e3181ac8364
dc.identifier.issn1522-0443
dc.identifier.issn1537-1611
dc.identifier.lattes4722881555254093
dc.identifier.lattes1346461670550428
dc.identifier.scopus2-s2.0-70349106396
dc.identifier.urihttp://hdl.handle.net/11449/71121
dc.language.isoeng
dc.relation.ispartofJournal of Clinical Neuromuscular Disease
dc.relation.ispartofsjr0,358
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectAnti-inflammatories
dc.subjectCarpal tunnel syndrome
dc.subjectSystematic review
dc.subjectantiinflammatory agent
dc.subjectbetamethasone acetate
dc.subjectbetamethasone sodium phosphate
dc.subjectcorticosteroid
dc.subjectmethylprednisolone
dc.subjectnonsteroid antiinflammatory agent
dc.subjectplacebo
dc.subjectprednisolone
dc.subjectsteroid
dc.subjectantiinflammatory activity
dc.subjectcarpal tunnel syndrome
dc.subjectclinical trial
dc.subjectcomparative study
dc.subjectdisease severity
dc.subjectelectroneurography
dc.subjectelectrophysiology
dc.subjectfollow up
dc.subjecthuman
dc.subjectlog rank test
dc.subjectneurophysiology
dc.subjectpriority journal
dc.subjectreview
dc.subjectsystematic review
dc.subjectAdrenal Cortex Hormones
dc.subjectAnti-Infective Agents
dc.subjectAnti-Inflammatory Agents, Non-Steroidal
dc.subjectCarpal Tunnel Syndrome
dc.subjectHumans
dc.subjectInjections, Intra-Articular
dc.subjectRandomized Controlled Trials as Topic
dc.subjectTreatment Outcome
dc.titleA systematic review of anti-inflammatories for mild to moderate carpal tunnel syndromeen
dc.typeResenha
dcterms.licensehttp://edmgr.ovid.com/spine/accounts/copyrightTransfer.pdf
unesp.author.lattes4722881555254093
unesp.author.lattes1346461670550428
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt

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Artigos - Saúde Pública - FMB
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