Effect of a meal feeding schedule on hepatic glycogen synthesis and gluconeogenesis in rats

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dc.contributor.authorBatista, M. R.
dc.contributor.authorCuri, R.
dc.contributor.authorLima, F. B.
dc.contributor.authorLopes, G.
dc.contributor.authorBazotte, R. B.
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Estadual de Maringá (UEM)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:20:17Z
dc.date.available2014-05-27T11:20:17Z
dc.date.issued2001-06-21
dc.description.abstractWe investigated the effect of a meal feeding schedule (MFS) on food intake, hepatic glycogen synthesis, hepatic capacity to produce glucose and glycemia in rats. The MFS comprised free access to food for a 2-hour period daily at a fixed mealtime (8.00-10.00 a.m.) for 13 days. The control group was composed of rats with free access to food from day 1 to 12, which were then starved for 22 h, refed with a single meal at 8.00-10.00 a.m. and starved again for another 22 h. All experiments were performed at the meal time (i.e. 8.00 a.m.). The MFS group exhibited increased food intake and higher glycogen synthase activity. Since gluconeogenesis from L-glutamine or L-alanine was not affected by MFS, we conclude that the increased food intake and higher glycogen synthase activity contributed to the better glucose maintenance showed by MFS rats at the fixed meal time. Copyright © 2001 National Science Council, ROC and S. Karger AG, Basel.en
dc.description.affiliationDepartment of Physiology and Biophysics State University of São Paulo, São Paulo
dc.description.affiliationDepartment of Pharmacy and Pharmacology State University of Maringá (DFF/UEM), Paraná 87020-900
dc.format.extent256-261
dc.identifierhttp://dx.doi.org/10.1159/000054041
dc.identifier.citationJournal of Biomedical Science, v. 8, n. 3, p. 256-261, 2001.
dc.identifier.doi10.1159/000054041
dc.identifier.issn1021-7770
dc.identifier.issn1423-0127
dc.identifier.scopus2-s2.0-0034986192
dc.identifier.urihttp://hdl.handle.net/11449/66534
dc.language.isoeng
dc.relation.ispartofJournal of Biomedical Science
dc.relation.ispartofjcr3.466
dc.relation.ispartofsjr1,302
dc.relation.ispartofsjr1,302
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectFeeding behavior
dc.subjectGlycemia
dc.subjectGlycogen synthase
dc.subjectHepatic gluconeogenesis
dc.subjectLiver metabolism
dc.subjectMeal feeding
dc.subjectMetabolic adaptations
dc.subjectUreagenesis
dc.subjectglycogen
dc.subjectglycogen synthase
dc.subjectanimal experiment
dc.subjectcontrolled study
dc.subjectenzyme activity
dc.subjectfeeding behavior
dc.subjectfood intake
dc.subjectgluconeogenesis
dc.subjectglucose blood level
dc.subjectglycogen liver level
dc.subjectglycogen synthesis
dc.subjectliver metabolism
dc.subjectmale
dc.subjectnonhuman
dc.subjectpriority journal
dc.subjectrat
dc.subjecturea cycle
dc.subjectAlanine
dc.subjectAnimals
dc.subjectBlood Glucose
dc.subjectFeeding Behavior
dc.subjectFood Deprivation
dc.subjectGluconeogenesis
dc.subjectGlucose
dc.subjectGlutamine
dc.subjectGlycogen Synthase
dc.subjectLactic Acid
dc.subjectLiver
dc.subjectLiver Glycogen
dc.subjectMale
dc.subjectRats
dc.subjectRats, Wistar
dc.subjectTime Factors
dc.subjectUrea
dc.titleEffect of a meal feeding schedule on hepatic glycogen synthesis and gluconeogenesis in ratsen
dc.typeArtigo
dcterms.licensehttp://www.springer.com/open+access/authors+rights

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