Microbiological assay for lomefloxacin in coated tablets

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dc.contributor.authorGomes, Greici Cristiani
dc.contributor.authorSalgado, Hérida Regina Nunes [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T13:24:41Z
dc.date.available2014-05-20T13:24:41Z
dc.date.issued2006-07-01
dc.description.abstractThe validation of a microbiological assay, applying cylinder plate method for determination of the activity of lomefloxacin in coated tablets is described. Using a strain of Bacillus subtilis ATCC 9372 as the test organism, lomefloxacin was measured in concentrations ranging from 2.0 to 8.0 mu g/mL. The method validation showed that it is linear (r = 0.9999), precise (relative standard deviation 1.15%), and accurate (it measured the added quantities). The excipients did not interfere in the determination. It was concluded that the microbiological assay is satisfactory for quantitation of lomefloxacin in tablets.en
dc.description.affiliationUNESP, Fac Ciências Farmaceut, BR-14801902 Araraquara, SP, Brazil
dc.description.affiliationUnespUNESP, Fac Ciências Farmaceut, BR-14801902 Araraquara, SP, Brazil
dc.format.extent1077-1079
dc.identifierhttp://www.ingentaconnect.com/content/aoac/jaoac/2006/00000089/00000004/art00024
dc.identifier.citationJournal of Aoac International. Gaithersburg: Aoac International, v. 89, n. 4, p. 1077-1079, 2006.
dc.identifier.issn1060-3271
dc.identifier.urihttp://hdl.handle.net/11449/7739
dc.identifier.wosWOS:000239470600025
dc.language.isoeng
dc.publisherAoac International
dc.relation.ispartofJournal of AOAC International
dc.relation.ispartofjcr1.087
dc.relation.ispartofsjr0,324
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.titleMicrobiological assay for lomefloxacin in coated tabletsen
dc.typeArtigo
dcterms.licensehttp://mc.manuscriptcentral.com/societyimages/aoac_jaoac/copyright.pdf
dcterms.rightsHolderAoac International
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Ciências Farmacêuticas, Araraquarapt

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