Avaliações bioquímicas séricas e hepáticas do extrato de yacon (Polymnia sonchifolia) Poepp. & Endl.

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dc.contributor.authorFernandes, A. A H [UNESP]
dc.contributor.authorBordon, J. G. [UNESP]
dc.contributor.authorBatistella, R. F. [UNESP]
dc.contributor.authorNascimento, S. M. [UNESP]
dc.contributor.authorSilva, M. S. [UNESP]
dc.contributor.authorAlves, M. J Q F [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:20:24Z
dc.date.available2014-05-27T11:20:24Z
dc.date.issued2002-01-01
dc.description.abstractYacon is a medicinal plant, the tuberous roots of which have been thought to contain a large amount of fructan (oligosaccharides). Purpose - The aim of paper was to study the effect of aqueous extracts of yacon on biochemical parameters of clinical importance in rats. The animals (male, wistar, weighing approximately 300g) were divided in 3 groups: G1(n=8)= water control; G2(n=8)= aqueous extract of roots (0,17g/100g/day); G3(n=8)= aqueous extract of leaves (25mg/100g/day). The serum samples were obtained after 30 days, and the biochemical parameters were measured. The livers were removed and homogenized in 0,01M phosphate buffer pH 7,0 and then the supernatant fractions were used for enzyme assay. Significantly increased serum glucose was observed in G2 (206,72±91,27 mg/dL). The groups G2 and G3 rats had higher (p<0,05) urea concentration, while creatinin level decreased (p<0,05). The serum albumin concentration showed a tendency to remain in G2 (2,44±0,45 g/dL) and G3 (2,84±0,50 g/dL). Aqueous extracts administration markedly decreased (p<0,05) the activities of ALT in the liver and greatly increased these enzymatic activities in blood. The serum alkaline phosphatase activity increased (p<0,05) in rats receiving the aqueous extract of root (192,75±20,95 U/dL), while aqueous extract of leaves reduced it (129,57±19,93 U/dL). The results indicated that the extract of yacon promoted changes of the biochemical parameters.en
dc.description.affiliationDepto. Quimica e Bioquimica/IB UNESP, Botucatu, SP
dc.description.affiliationUnespDepto. Quimica e Bioquimica/IB UNESP, Botucatu, SP
dc.format.extent30-34
dc.identifierhttp://www.ibb.unesp.br/Home/Departamentos/Botanica/RBPM-RevistaBrasileiradePlantasMedicinais/artigo_6_v4_n2.pdf
dc.identifier.citationRevista Brasileira de Plantas Medicinais, v. 4, n. 2, p. 30-34, 2002.
dc.identifier.file2-s2.0-0036081788.pdf
dc.identifier.issn1516-0572
dc.identifier.scopus2-s2.0-0036081788
dc.identifier.urihttp://hdl.handle.net/11449/66786
dc.language.isopor
dc.relation.ispartofRevista Brasileira de Plantas Medicinais
dc.relation.ispartofsjr0,199
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectAsteraceae
dc.subjectFructans
dc.subjectLiver
dc.subjectMedicinal plants
dc.subjectMetabolism
dc.subjectSerum protein
dc.subjectTherapies alternatives
dc.subjectalkaline phosphatase
dc.subjectfructan
dc.subjectoligosaccharide
dc.subjectplant extract
dc.subjectpolymnia sonchifolia extract
dc.subjectunclassified drug
dc.subjectanimal cell
dc.subjectaqueous solution
dc.subjectbiochemical composition
dc.subjectblood sampling
dc.subjectenzyme activity
dc.subjectenzyme assay
dc.subjectliver parenchyma
dc.subjectmedicinal plant
dc.subjectnonhuman
dc.subjectplant leaf
dc.subjectplant root
dc.subjectrat
dc.titleAvaliações bioquímicas séricas e hepáticas do extrato de yacon (Polymnia sonchifolia) Poepp. & Endl.pt
dc.title.alternativeSerum and hepatic biochemical evaluations of yacon (Polymnia sonchifolia) extracten
dc.typeArtigo
dcterms.licensehttp://www.scielo.br/revistas/rbpm/paboutj.htm#03
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Biociências, Botucatupt

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