Effects of a continuous rate infusion of butorphanol in isoflurane-anesthetized horses on cardiorespiratory parameters, recovery quality, gastrointestinal motility and serum cortisol concentrations

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dc.contributor.authorDias, Bianca Paludeto [UNESP]
dc.contributor.authorAraújo, Marcelo Augusto de
dc.contributor.authorDeschk, Maurício [UNESP]
dc.contributor.authorTrein, Thomas Alexander [UNESP]
dc.contributor.authorPinheiro, Nirmem Carlos [UNESP]
dc.contributor.authorPerri, Silvia Helena Venturolli [UNESP]
dc.contributor.authorRodrigues, Celso Antônio [UNESP]
dc.contributor.authorSantos, Paulo Sergio Patto dos [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionFederal University of Mato Grosso do Sul Faculty of Veterinary Medicine and Animal Science
dc.date.accessioned2015-02-02T12:39:20Z
dc.date.available2015-02-02T12:39:20Z
dc.date.issued2014-12-01
dc.description.abstractPURPOSE: To assess the cardiorespiratory parametes, recovery, gastrointestinal motility and serum cortisol concentrations in horses anesthetized with isoflurane with or without a continuous rate infusion (CRI) of butorphanol for orchiectomy. METHODS: Twelve adult, intact, male horses weighing 332 ± 55 kg were included in the study. Xilazine was administered as premedication. Anesthesia was induced with ketamine and midazolam and maintained with isoflurane. Butorphanol (0.025 mg kg-1 bolus) or an equivalent volume of saline (0.9%) was given intravenously followed by a CRI of butorphanol (BG) (13 µg kg-1 hour-1) or saline (CG). Cardiorespiratory variables were recorded before (T0) and every 15 minutes for 75 minutes after the start of infusion. Serum cortisol concentration was measured at T0 and 60 minutes, and 30 minutes and 19 hours after the horse stood up. Recovery from anesthesia was evaluated using a scoring system. Gastrointestinal motility was evaluated before anesthesia and during 24 hours after recovery. RESULTS: There were no significant differences between groups in cardiopulmonary variables, or recovery scores or serum cortisol concentrations. A reduction in gastrointestinal motility was recorded for 60 minutes in BG. CONCLUSIONS: Continuous rate infusion of butorphanol in horses anesthetized with isoflurane did not adversely affect the cardiopulmonary variables monitored, or recovery scores. A small but statistically significant reduction in gastrointestinal motility occurred in the butorphanol group.en
dc.description.affiliationSao Paulo State University Faculty of Veterinary Medicine
dc.description.affiliationFederal University of Mato Grosso do Sul Faculty of Veterinary Medicine and Animal Science
dc.description.affiliationUNESP Faculty of Veterinary Medicine
dc.description.affiliationUNESP Faculty of Veterinary Medicine Department of Clinical, Surgey and Animal Reproduction
dc.description.affiliationUNESP Faculty of Veterinary Medicine Department of Support, Animal Production and Health
dc.description.affiliationUNESP Faculty of Veterinary Medicine Department of Surgery and Anesthesiology
dc.description.affiliationUNESP Faculty of Veterinary Medicine Department of Clinical, Surgery and Animal Reproduction
dc.description.affiliationUnespSao Paulo State University Faculty of Veterinary Medicine
dc.description.affiliationUnespUNESP Faculty of Veterinary Medicine
dc.description.affiliationUnespUNESP Faculty of Veterinary Medicine Department of Clinical, Surgey and Animal Reproduction
dc.description.affiliationUnespUNESP Faculty of Veterinary Medicine Department of Support, Animal Production and Health
dc.description.affiliationUnespUNESP Faculty of Veterinary Medicine Department of Surgery and Anesthesiology
dc.description.affiliationUnespUNESP Faculty of Veterinary Medicine Department of Clinical, Surgery and Animal Reproduction
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.format.extent801-806
dc.identifierhttp://dx.doi.org/10.1590/S0102-86502014001900006
dc.identifier.citationActa Cirurgica Brasileira. Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, v. 29, n. 12, p. 801-806, 2014.
dc.identifier.doi10.1590/S0102-86502014001900006
dc.identifier.fileS0102-86502014001200801.pdf
dc.identifier.issn0102-8650
dc.identifier.lattes5331938962896664
dc.identifier.orcid0000-0002-8535-5569
dc.identifier.scieloS0102-86502014001200801
dc.identifier.urihttp://hdl.handle.net/11449/114209
dc.language.isoeng
dc.publisherSociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
dc.relation.ispartofActa Cirurgica Brasileira
dc.relation.ispartofjcr0.933
dc.relation.ispartofsjr0,395
dc.rights.accessRightsAcesso aberto
dc.sourceSciELO
dc.subjectBlood Gas Analysisen
dc.subjectAnalgesics, Opioiden
dc.subjectAnesthesia, Inhalationen
dc.subjectOrchiectomyen
dc.subjectHorsesen
dc.titleEffects of a continuous rate infusion of butorphanol in isoflurane-anesthetized horses on cardiorespiratory parameters, recovery quality, gastrointestinal motility and serum cortisol concentrationsen
dc.typeArtigo
unesp.author.lattes5331938962896664[8]
unesp.author.orcid0000-0002-8535-5569[8]

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