Understanding Clinical Significance in Rehabilitation: A Primer for Researchers and Clinicians

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dc.contributor.authorArmijo-Olivo, Susan
dc.contributor.authorde Castro-Carletti, Ester Moreira
dc.contributor.authorCalixtre, Letícia Bojikian
dc.contributor.authorde Oliveira-Souza, Ana Izabela Sobral
dc.contributor.authorMohamad, Norazlin
dc.contributor.authorFuentes, Jorge
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.date.accessioned2022-04-29T08:46:18Z
dc.date.available2022-04-29T08:46:18Z
dc.date.issued2022-01-01
dc.description.abstractABSTRACT: The objective of this review was to summarize the concept of clinical significance and associated methods focusing on the area of rehabilitation to provide a resource to rehabilitation researchers and clinicians. Studies were searched on electronic databases from inception until July 28, 2020, with no date or language limits. Manual searches as well as Scopus forward citation for relevant references were performed. Narrative synthesis of study results was performed. Definitions of the concepts related to clinical significance, ways of calculating, and interpreting each method were provided using rehabilitation examples. An explanation of methods to evaluate clinical significance (distribution, anchor, and opinion-based methods) and their advantages and disadvantages were also provided. Considering the limitations of statistical significance in assuring meaningfulness of results, clinical interpretation of research outcomes and the report of clinical significance in intervention trials should be a priority in rehabilitation research. When possible, the use of multiple methods (distribution, anchor, and opinion based) is recommended. Thus, clinical researchers are encouraged to present results in a manner that allow the rehabilitation professionals to easily interpret and implement those results in their clinical practice.en
dc.description.affiliationFrom the University of Applied Sciences Osnabrück, Faculty of Economics and Social Sciences, Osnabrück, Germany (SA-O, AISO-S); Faculties of Rehabilitation Medicine and Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada (SA-O); Postgraduate Program in Human Movement Sciences, Methodist University of Piracicaba (UNIMEP), Piracicaba, Brazil (EMC-C); Department of Dental Materials and Prosthodontics, Araraquara Dental School, São Paulo State University (UNESP), Araraquara, Brazil (LBC); Graduate Program in Neuropsychiatry and Behavioral Sciences, Federal University of Pernambuco, Pernambuco, Brazil (AISO-S); Faculty of Rehabilitation Medicine, Department of Physical Therapy, University of Alberta, Edmonton, Alberta, Canada (NM); Faculty of Health Science, Center of Physiotherapy, Universiti Teknologi MARA, Puncak Alam, Malaysia (NM); and Faculty of Health Sciences, Department of Physical Therapy, Clinical Research Lab, Catholic University of Maule, Talca, Chile (JF)
dc.description.sponsorshipEunice Kennedy Shriver National Institute of Child Health and Human Development
dc.description.sponsorshipIdEunice Kennedy Shriver National Institute of Child Health and Human Development: P2C HD065702
dc.format.extent64-77
dc.identifierhttp://dx.doi.org/10.1097/PHM.0000000000001799
dc.identifier.citationAmerican journal of physical medicine & rehabilitation, v. 101, n. 1, p. 64-77, 2022.
dc.identifier.doi10.1097/PHM.0000000000001799
dc.identifier.issn1537-7385
dc.identifier.scopus2-s2.0-85122840123
dc.identifier.urihttp://hdl.handle.net/11449/231593
dc.language.isoeng
dc.relation.ispartofAmerican journal of physical medicine & rehabilitation
dc.sourceScopus
dc.titleUnderstanding Clinical Significance in Rehabilitation: A Primer for Researchers and Cliniciansen
dc.typeResenha

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