Respiratory pressures and expiratory peak flow rate of patients undergoing coronary artery bypass graft surgery

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dc.contributor.authorGimenes, Camila [UNESP]
dc.contributor.authorGodoy, Irma de [UNESP]
dc.contributor.authorPadovani, Carlos Roberto [UNESP]
dc.contributor.authorGimenes, Rodrigo [UNESP]
dc.contributor.authorOkoshi, Marina Politi [UNESP]
dc.contributor.authorOkoshi, Katashi [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T13:48:08Z
dc.date.available2014-05-20T13:48:08Z
dc.date.issued2012-09-01
dc.description.abstractBackground: To evaluate clinical and laboratorial parameters that predict decreased respiratory function in patients subjected to coronary artery bypass graft surgery (CABG).Material/Methods: This was a prospective study evaluating 61 patients subjected to CABG with cardiopulmonary bypass, median sternotomy, and under mechanical ventilation for up to 24 h. One day before surgery, clinical information was recorded. Maximal inspiratory (MIP) and expiratory (MEP) pressures, and expiratory peak flow rate (EPFR) values were assessed 1 day before surgery and on the fifth postoperative day. Student's t test, 2-way ANOVA, Pearson's linear correlation, and logistic regression were used for statistical analysis.Results: Patients were 63 +/- 10 years old, 67% males. Arterial hypertension was found in 75.4% of the patients, diabetes in 31.2%, dyslipidemia in 63.9%, tabagism in 25%, and chronic obstructive pulmonary disease (COPD) in 16.4%. Previous myocardial infarction was found in 67%. Preoperative hemoglobin levels were 12.8 +/- 1.71 g/dL. Older individuals had lower preoperative MEP and EPFR values. Preoperatively, positive association was found between hemoglobin levels and maximal respiratory pressures and EPFR values. Patients with both class III angina and COPD presented higher reductions in pulmonary pressures between the preoperative period and the 5th postoperative day.Conclusions: Older age and low hemoglobin levels are associated with preoperative low maximal respiratory pressures and EPFR. The combination of severe angina and COPD results in higher postoperative reduction of maximal respiratory pressures for patients who underwent CABG.en
dc.description.affiliationSão Paulo State Univ, UNESP, Botucatu Med Sch, Dept Internal Med, São Paulo, Brazil
dc.description.affiliationSão Paulo State Univ, UNESP, Biosci Inst, Dept Biostat, São Paulo, Brazil
dc.description.affiliationUnespSão Paulo State Univ, UNESP, Botucatu Med Sch, Dept Internal Med, São Paulo, Brazil
dc.description.affiliationUnespSão Paulo State Univ, UNESP, Biosci Inst, Dept Biostat, São Paulo, Brazil
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipFundação para o Desenvolvimento da UNESP (FUNDUNESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipIdCNPq: 304998/2009-5
dc.description.sponsorshipIdCNPq: 305013/2009-0
dc.format.extentCR558-CR563
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/22936191
dc.identifier.citationMedical Science Monitor. Smithtown: Int Scientific Literature, Inc, v. 18, n. 9, p. CR558-CR563, 2012.
dc.identifier.issn1234-1010
dc.identifier.lattes5079454858778041
dc.identifier.lattes4463138671998432
dc.identifier.lattes1590971576309420
dc.identifier.urihttp://hdl.handle.net/11449/17167
dc.identifier.wosWOS:000308607100010
dc.language.isoeng
dc.publisherInt Scientific Literature, Inc
dc.relation.ispartofMedical Science Monitor
dc.relation.ispartofsjr0,619
dc.rights.accessRightsAcesso aberto
dc.sourceWeb of Science
dc.subjectcoronary artery bypass graften
dc.subjectpre- and intra-operative factorsen
dc.subjectmaximal inspiratory pressureen
dc.subjectmaximal expiratory pressureen
dc.subjectexpiratory peak flow rateen
dc.titleRespiratory pressures and expiratory peak flow rate of patients undergoing coronary artery bypass graft surgeryen
dc.typeArtigo
dcterms.rightsHolderInt Scientific Literature, Inc
unesp.author.lattes5079454858778041
unesp.author.lattes4463138671998432
unesp.author.lattes1590971576309420
unesp.author.lattes8727897080522289[3]
unesp.author.orcid0000-0002-7719-9682[3]
unesp.author.orcid0000-0001-8980-8839[6]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt

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Artigos - Clínica Médica - FMB