Effect of fluoride intake on carbohydrate metabolism, glucose tolerance, and insulin signaling

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dc.contributor.authorChiba, Fernando Yamamoto [UNESP]
dc.contributor.authorGarbin, Clea Adas Saliba [UNESP]
dc.contributor.authorSumida, Doris Hissako [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2013-09-30T18:29:11Z
dc.date.accessioned2014-05-20T13:43:01Z
dc.date.available2013-09-30T18:29:11Z
dc.date.available2014-05-20T13:43:01Z
dc.date.issued2012-07-01
dc.description.abstractFluoride is known to cause both local and systemic alterations in animals and humans, such as dental fluorosis and disturbances in glucose homeostasis. The effects of fluoride are dose dependent and can produce decreased insulin secretion, inhibition of glycolysis, glycogen depletion, hyperglycemia, and insulin resistance. Because excessive ingestion of fluoride during tooth brushing can lead to deterioration in health, the use of low-fluoride dentifrices is recommended for young children with diabetes.en
dc.description.affiliationUNESP Univ Estadual Paulista, Dent Sch Aracatuba, Dept Basic Sci, BR-16015050 Aracatuba, SP, Brazil
dc.description.affiliationUNESP Univ Estadual Paulista, Dent Sch Aracatuba, Dept Child & Social Dent, BR-16015050 Aracatuba, SP, Brazil
dc.description.affiliationUnespUNESP Univ Estadual Paulista, Dent Sch Aracatuba, Dept Basic Sci, BR-16015050 Aracatuba, SP, Brazil
dc.description.affiliationUnespUNESP Univ Estadual Paulista, Dent Sch Aracatuba, Dept Child & Social Dent, BR-16015050 Aracatuba, SP, Brazil
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipPró-Reitoria de Pesquisa da UNESP (PROPe UNESP)
dc.description.sponsorshipFundação para o Desenvolvimento da UNESP (FUNDUNESP)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipIdFAPESP: 09/00086-7
dc.description.sponsorshipIdFAPESP: 10/10664-5
dc.format.extent236-241
dc.identifierhttp://www.fluorideresearch.org/453Pt2/files/FJ2012_v45_n3Pt2_p236-241_pq.pdf
dc.identifier.citationFluoride. Ocean View: Int Soc Fluoride Research, v. 45, n. 3, p. 236-241, 2012.
dc.identifier.issn0015-4725
dc.identifier.lattes8275401688702343
dc.identifier.lattes4419158525709686
dc.identifier.orcid0000-0001-5069-8812
dc.identifier.urihttp://hdl.handle.net/11449/14970
dc.identifier.wosWOS:000314143900002
dc.language.isoeng
dc.publisherInt Soc Fluoride Research
dc.relation.ispartofFluoride
dc.relation.ispartofjcr1.438
dc.relation.ispartofsjr0,429
dc.rights.accessRightsAcesso aberto
dc.sourceWeb of Science
dc.subjectChildhood diabetesen
dc.subjectDiabetes mellitusen
dc.subjectGlucose homeostasisen
dc.subjectHyperglycemiaen
dc.subjectInsulin resistanceen
dc.subjectLow-fluoride dentifricesen
dc.titleEffect of fluoride intake on carbohydrate metabolism, glucose tolerance, and insulin signalingen
dc.typeResenha
dcterms.rightsHolderInt Soc Fluoride Research
unesp.author.lattes8275401688702343
unesp.author.lattes4419158525709686[2]
unesp.author.orcid0000-0003-4406-405X[1]
unesp.author.orcid0000-0001-5069-8812[2]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Odontologia, Araçatubapt

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Artigos - Ciências Básicas - FOA
Artigos - Odontologia Infantil e Social - FOA