Impact of the training program on lipid profile and cardiac health

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dc.contributor.authorBurneiko, R. C.
dc.contributor.authorDiniz, Y. S.
dc.contributor.authorFaine, L. A.
dc.contributor.authorGalhardi, C. M.
dc.contributor.authorPadovani, C. R.
dc.contributor.authorNovelli, ELB
dc.contributor.authorCicogna, A. C.
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T15:25:47Z
dc.date.available2014-05-20T15:25:47Z
dc.date.issued2004-01-01
dc.description.abstractThe aim of this study was to investigate the effects of training programs on serum lipid profile and myocardial oxidative stress. Male Wistar rats (2 mo-old) were divided into three groups (n=8): sedentary (S), loadless trained (T) and trained-overload 2% body weight (TL). T and TL were trained through swimming for 9 weeks. T and TL rats had increased myocardial lipoperoxide (TBA) and lipid hydroperoxide (HP), whereas HP was higher in TL than in T animals. Superoxide dismutase (SOD) activities were lowest in TL. Myocardial glutathione peroxidase (GSH-Px) was lower in TL than in T and S rats. TL decreased HDL-cholesterol and increased LDL-cholesterol. The serum lactate dehydrogenase and TBA were increased, while SOD and GSH-Px activities were decreased in TL rats. Loadless training was able to improve HDL-cholesterol and to reduce LDL-cholesterol. In conclusion, the loadless training program induced beneficial effects on lipid profile, while overload training induced dyslipidemic profile that was associated with serum oxidative stress. The overload training program was deleterious relative to loadless training program, increasing myocardial oxidative stress.en
dc.description.affiliationUniv Estadual Paulista, Inst Biociencias, Dept Quim & Bioquim, BR-18618000 São Paulo, Brazil
dc.description.affiliationUNESP, Fac Med, São Paulo, Brazil
dc.description.affiliationUNESP, Inst Biol Sci, Dept Biostat, São Paulo, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Inst Biociencias, Dept Quim & Bioquim, BR-18618000 São Paulo, Brazil
dc.description.affiliationUnespUNESP, Fac Med, São Paulo, Brazil
dc.description.affiliationUnespUNESP, Inst Biol Sci, Dept Biostat, São Paulo, Brazil
dc.format.extent53-59
dc.identifierhttp://dx.doi.org/10.4067/S0716-97602004000100006
dc.identifier.citationBiological Research. Santiago: Sociedad Biolgia Chile, v. 37, n. 1, p. 53-59, 2004.
dc.identifier.doi10.4067/S0716-97602004000100006
dc.identifier.fileWOS000221605400005.pdf
dc.identifier.issn0716-9760
dc.identifier.lattes8727897080522289
dc.identifier.scieloS0716-97602004000100006
dc.identifier.urihttp://hdl.handle.net/11449/36137
dc.identifier.wosWOS:000221605400005
dc.language.isoeng
dc.publisherSociedad Biolgia Chile
dc.relation.ispartofBiological Research
dc.relation.ispartofjcr2.357
dc.relation.ispartofsjr0,654
dc.rights.accessRightsAcesso aberto
dc.sourceWeb of Science
dc.subjecttrainingpt
dc.subjectlipid profilept
dc.subjectoxidative stresspt
dc.subjectheartpt
dc.subjectserumpt
dc.titleImpact of the training program on lipid profile and cardiac healthen
dc.typeArtigo
dcterms.licensehttp://www.scielo.cl/revistas/bres/iaboutj.htm
dcterms.rightsHolderSociedad Biolgia Chile
unesp.author.lattes8727897080522289[5]
unesp.author.lattes9418970103564137[7]
unesp.author.orcid0000-0002-7719-9682[5]
unesp.author.orcid0000-0001-8741-1336[4]
unesp.author.orcid0000-0002-4402-6523[7]
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Biociências, Botucatupt

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Artigos - Química e Bioquímica - IBB