Physiological Concentrations of Acute-Phase Proteins and Immunoglobulins in Equine Synovial Fluid

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dc.contributor.authorBasile, Roberta C. [UNESP]
dc.contributor.authorFerraz, Guilherme C. [UNESP]
dc.contributor.authorCarvalho, Marsel P. [UNESP]
dc.contributor.authorAlbernaz, Raquel M. [UNESP]
dc.contributor.authorAraújo, Renatha A. [UNESP]
dc.contributor.authorFagliari, José J. [UNESP]
dc.contributor.authorQueiroz-Neto, Antonio [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:28:34Z
dc.date.available2014-05-27T11:28:34Z
dc.date.issued2013-03-01
dc.description.abstractSynovial fluid (SF) is capable of reflecting infectious, immunological, or inflammatory joint conditions in horses by altering its composition and appearance. Although plasma and SF compositions are quantitatively different, this latter compartment reflects changes in plasma macromolecules. Therefore, changes in serum immunoglobulin protein concentrations tend also to alter intracapsular levels. Therefore, it is necessary to know the physiological concentrations of proteins present in SF. The aim of this study was to determine the levels of total protein, albumin, transferrin, haptoglobin, α1-acid glycoprotein, ceruloplasmin, and immunoglobulins A and G in SF of six healthy horses. The synovial proteinogram was obtained by sodium dodecyl sulfate polyacrylamide gel electrophoresis. The SF proteins reached a maximum of 25% of serum concentrations, varying inversely with molecular weight of the protein, except for the ceruloplasmin. © 2013 Elsevier Inc.en
dc.description.affiliationFaculdade de Ciências Agrárias e Veterinárias Departamento de Morfologia e Fisiologia Animal Lab. de Farmacologia e Fisiologia do Exercício Equino-LAFEQ, Universidade Estadual Paulista (UNESP), Campus de Jaboticabal, Jaboticabal, São Paulo
dc.description.affiliationFaculdade de Ciências Agrárias e Veterinárias Departamento de Clínica e Cirurgia Veterinária Universidade Estadual Paulista (UNESP), Campus de Jaboticabal, Jaboticabal, São Paulo
dc.description.affiliationUnespFaculdade de Ciências Agrárias e Veterinárias Departamento de Morfologia e Fisiologia Animal Lab. de Farmacologia e Fisiologia do Exercício Equino-LAFEQ, Universidade Estadual Paulista (UNESP), Campus de Jaboticabal, Jaboticabal, São Paulo
dc.description.affiliationUnespFaculdade de Ciências Agrárias e Veterinárias Departamento de Clínica e Cirurgia Veterinária Universidade Estadual Paulista (UNESP), Campus de Jaboticabal, Jaboticabal, São Paulo
dc.format.extent201-204
dc.identifierhttp://dx.doi.org/10.1016/j.jevs.2012.05.075
dc.identifier.citationJournal of Equine Veterinary Science, v. 33, n. 3, p. 201-204, 2013.
dc.identifier.doi10.1016/j.jevs.2012.05.075
dc.identifier.file2-s2.0-84874293618.pdf
dc.identifier.issn0737-0806
dc.identifier.scopus2-s2.0-84874293618
dc.identifier.urihttp://hdl.handle.net/11449/74669
dc.identifier.wosWOS:000315763400012
dc.language.isoeng
dc.relation.ispartofJournal of Equine Veterinary Science
dc.relation.ispartofjcr0.880
dc.relation.ispartofsjr0,390
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectElectrophoresis
dc.subjectHorse
dc.subjectJoint
dc.subjectProteinogram
dc.subjectSDS-polyacrylamide gel electrophoresis
dc.subjectEquidae
dc.titlePhysiological Concentrations of Acute-Phase Proteins and Immunoglobulins in Equine Synovial Fluiden
dc.typeArtigo
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
unesp.author.orcid0000-0002-6463-6628[2]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Ciências Agrárias e Veterinárias, Jaboticabalpt

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Artigos - Morfologia e Fisiologia Animal - FCAV
Artigos - Clínica e Cirurgia Veterinária - FCAV