Ethanol's Action Mechanisms in the Brain: From Lipid General Alterations to Specific Protein Receptor Binding

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dc.contributor.authorMarin, M. T. [UNESP]
dc.contributor.authorMorais-Silva, G. [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2019-10-06T15:19:44Z
dc.date.available2019-10-06T15:19:44Z
dc.date.issued2017-02-23
dc.description.abstractEthanol is the most popular addictive substance used in the word. Its small and relatively simple structure facilitates its access to brain tissues and binding to many sites. This relatively unspecific action can partially explain the myriad of effects and also the dose-dependent actions of this drug. This chapter highlights ethanol action mechanisms from the early classical studies, showing ethanol effects on lipid neuronal membranes, to recent studies, showing specific binding to many protein receptor targets.en
dc.description.affiliationSão Paulo State University (UNESP)
dc.description.affiliationUnespSão Paulo State University (UNESP)
dc.format.extent149-161
dc.identifierhttp://dx.doi.org/10.1016/B978-0-12-805373-7.00016-5
dc.identifier.citationAddictive Substances and Neurological Disease: Alcohol, Tobacco, Caffeine, and Drugs of Abuse in Everyday Lifestyles, p. 149-161.
dc.identifier.doi10.1016/B978-0-12-805373-7.00016-5
dc.identifier.scopus2-s2.0-85054355376
dc.identifier.urihttp://hdl.handle.net/11449/186916
dc.language.isoeng
dc.relation.ispartofAddictive Substances and Neurological Disease: Alcohol, Tobacco, Caffeine, and Drugs of Abuse in Everyday Lifestyles
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectCys-loop ligand-gated ion channels superfamily
dc.subjectAction mechanism
dc.subjectCentral nervous system
dc.subjectEthanol binding
dc.subjectEthanol receptor
dc.subjectNeurotransmitter
dc.titleEthanol's Action Mechanisms in the Brain: From Lipid General Alterations to Specific Protein Receptor Bindingen
dc.typeCapítulo de livro

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