Dimensional correlates of poor insight in obsessive-compulsive disorder

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dc.contributor.authorJakubovski, Ewgeni
dc.contributor.authorPittenger, Christopher
dc.contributor.authorTorres, Albina Rodrigues [UNESP]
dc.contributor.authorFontenelle, Leonardo Franklin
dc.contributor.authordo Rosario, Maria Conceicao
dc.contributor.authorFerrão, Ygor Arzeno
dc.contributor.authorde Mathis, Maria Alice
dc.contributor.authorMiguel, Euripedes Constantino
dc.contributor.authorBloch, Michael H.
dc.contributor.institutionUniversity of Heidelberg
dc.contributor.institutionYale University School of Medicine
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade Federal do Rio de Janeiro (UFRJ)
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.contributor.institutionUniversidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA)
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.date.accessioned2014-05-27T11:25:58Z
dc.date.available2014-05-27T11:25:58Z
dc.date.issued2011-08-15
dc.description.abstractBackground: Cross-sectional studies have associated poor insight in patients with obsessive-compulsive disorder (OCD) with increased OCD symptom severity, earlier age of onset, comorbid depression, and treatment response. The goal of this current study was to examine the relationship between dimensions of OCD symptomatology and insight in a large clinical cohort of Brazilian patients with OCD. We hypothesized that poor insight would be associated with total symptom severity as well as with hoarding symptoms severity, specifically. Methods: 824 outpatients underwent a detailed clinical assessment for OCD, including the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS), the Dimensional Yale-Brown Obsessive-Compulsive Scale (DY-BOCS), the Brown Assessment of Beliefs Scale (BABS), a socio-demographic questionnaire, and the Structured Clinical Interview for axis I DSM-IV disorders (SCID-P). Tobit regression models were used to examine the association between level of insight and clinical variables of interest. Results: Increased severity of current and worst-ever hoarding symptoms and higher rate of unemployment were associated with poor insight in OCD after controlling for current OCD severity, age and gender. Poor insight was also correlated with increased severity of current OCD symptoms. Conclusion: Hoarding and overall OCD severity were significantly but weakly associated with level of insight in OCD patients. Further studies should examine insight as a moderator and mediator of treatment response in OCD in both behavioral therapy and pharmacological trials. Behavioral techniques aimed at enhancing insight may be potentially beneficial in OCD, especially among patients with hoarding. © 2011.en
dc.description.affiliationDepartment of Psychology University of Heidelberg
dc.description.affiliationDepartment of Psychiatry Yale University School of Medicine, New Haven, CT
dc.description.affiliationYale Child Study Center Yale University School of Medicine, New Haven, CT
dc.description.affiliationDepartamento de Neurologia, Psicologia e Psiquiatria Univ Estadual Paulista (UNESP)
dc.description.affiliationInstitute of Psychiatry Universidade Federal do Rio de Janeiro
dc.description.affiliationDepartamento de Psiquiatria Universidade Federal de São Paulo
dc.description.affiliationDepartment of Psychiatry Universidade Federal de Ciências da Saúde de Porto Alegre
dc.description.affiliationDepartment of Psychiatry Faculdade de Medicina Universidade de São Paulo
dc.description.affiliationUnespDepartamento de Neurologia, Psicologia e Psiquiatria Univ Estadual Paulista (UNESP)
dc.format.extent1677-1681
dc.identifierhttp://dx.doi.org/10.1016/j.pnpbp.2011.05.012
dc.identifier.citationProgress in Neuro-Psychopharmacology and Biological Psychiatry, v. 35, n. 7, p. 1677-1681, 2011.
dc.identifier.doi10.1016/j.pnpbp.2011.05.012
dc.identifier.issn0278-5846
dc.identifier.issn1878-4216
dc.identifier.lattes3837157956819433
dc.identifier.scopus2-s2.0-79961127104
dc.identifier.urihttp://hdl.handle.net/11449/72605
dc.language.isoeng
dc.relation.ispartofProgress in Neuro-Psychopharmacology and Biological Psychiatry
dc.relation.ispartofjcr4.185
dc.relation.ispartofsjr1,714
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectHoarding
dc.subjectInsight
dc.subjectObsessive-compulsive disorder
dc.subjectSymptom dimension
dc.subjectadult
dc.subjectage distribution
dc.subjectBrown Assessment of Belief Scale
dc.subjectchild
dc.subjectclinical assessment tool
dc.subjectcomorbidity
dc.subjectcontrolled study
dc.subjectdepression
dc.subjectdimensional yale brown obsessive compulsive scale
dc.subjectdisease duration
dc.subjectdisease severity
dc.subjectemployment status
dc.subjectfemale
dc.subjecthuman
dc.subjectintrospection
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmarriage
dc.subjectobsessive compulsive disorder
dc.subjectonset age
dc.subjectpreschool child
dc.subjectquestionnaire
dc.subjectschool child
dc.subjectsex difference
dc.subjectStructured Clinical Interview for DSM Disorders
dc.subjectsymptomatology
dc.subjecttreatment response
dc.subjectunemployment
dc.subjectYale Brown Obsessive Compulsive Scale
dc.subjectAdult
dc.subjectBrazil
dc.subjectCohort Studies
dc.subjectDelusions
dc.subjectDisease Progression
dc.subjectFemale
dc.subjectHumans
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectObsessive Hoarding
dc.subjectObsessive-Compulsive Disorder
dc.subjectPerception
dc.subjectPsychiatric Status Rating Scales
dc.subjectQuestionnaires
dc.subjectTime Factors
dc.subjectYoung Adult
dc.titleDimensional correlates of poor insight in obsessive-compulsive disorderen
dc.typeArtigo
dcterms.licensehttp://www.elsevier.com/about/open-access/open-access-policies/article-posting-policy
unesp.author.lattes3837157956819433[3]
unesp.author.orcid0000-0003-1072-5008[3]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt

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