Effects of a ferment soy product on the adipocyte area reduction and dyslipidemia control in hypercholesterolemic adult male rats

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dc.contributor.authorCheik, Nadia Carla
dc.contributor.authorRossi, Elizeu Antonio [UNESP]
dc.contributor.authorFernandes Guerra, Ricardo Luis
dc.contributor.authorTenorio, Neuli Maria
dc.contributor.authorOller do Nascimento, Claudia Maria
dc.contributor.authorViana, Fabiana Pavan
dc.contributor.authorJovenasso Manzoni, Marla Simone
dc.contributor.authorCarlos, Iracilda Zeppone [UNESP]
dc.contributor.authorda Silva, Patricia Leao
dc.contributor.authorVendramini, Regina Célia [UNESP]
dc.contributor.authorDamaso, Ana Raimunda
dc.contributor.institutionUniversidade Federal de Uberlândia (UFU)
dc.contributor.institutionUniversidade Federal de São Carlos (UFSCar)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2014-05-20T13:23:37Z
dc.date.available2014-05-20T13:23:37Z
dc.date.issued2008-12-16
dc.description.abstractBackground: Available data on the effects of a fermented soy product enriched with Enterococcus faecium and Lactobacillus Jugurti on circulating lipids and adiposity are not completely settled. This study aimed to observe the effects of a fermented soy product enriched with Enterococcus faecium and Lactobacillus Jugurti on central obesity and dyslipidemia control in Wistar adult male rats.Methods: Over a period of 8 weeks, animals had ad libitum food intake and water consumption as well as body weight and food consumption was monitored. The animals were assigned to four different experimental groups: Control Group (C); Control + Fermented Product Group (CPF); Hypercholesterolemic diet group (H); and Hypercholesterolemic + Fermented Product Group (HPF). The HPF and CPF groups received an intragastric administration of 1 ml of fermented product daily. After the experimental period the animals were killed by decapitation, blood was collected to measure cholesterol, triglycerides and HDL-cholesterol plasma concentration. Adipocyte circumference, lipolysis and lipogenis rates were measures using epididymal and retroperitoneal white adipose tissues.Results: The results demonstrated that 1 ml/day/rat of the fermented soy product promoted important benefits such as reduced cholesterolemia in hypercholesterolemic diet group and the adipocyte circumference in both control and hypercholesterolemic diet group.Conclusion: The fermented soy product enriched with Enterococcus faecium and Lactobacillus Jugurti decreased circulating lipids levels and reduced adipocyte area in rats.en
dc.description.affiliationUniv Fed Uberlandia, BR-38400 Uberlandia, MG, Brazil
dc.description.affiliationUniv Fed Sao Carlos, São Paulo, Brazil
dc.description.affiliationUniv Estadual Paulista, São Paulo, Brazil
dc.description.affiliationUniv Fed São Paulo, Escola Paulista Med, São Paulo, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, São Paulo, Brazil
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.format.extent9
dc.identifierhttp://dx.doi.org/10.1186/1476-511X-7-50
dc.identifier.citationLipids In Health and Disease. London: Biomed Central Ltd., v. 7, p. 9, 2008.
dc.identifier.doi10.1186/1476-511X-7-50
dc.identifier.fileWOS000263122400001.pdf
dc.identifier.issn1476-511X
dc.identifier.lattes3242858535763793
dc.identifier.lattes1730146818754269
dc.identifier.lattes7641979287850489
dc.identifier.urihttp://hdl.handle.net/11449/7151
dc.identifier.wosWOS:000263122400001
dc.language.isoeng
dc.publisherBiomed Central Ltd.
dc.relation.ispartofLipids in Health and Disease
dc.relation.ispartofjcr2.663
dc.rights.accessRightsAcesso aberto
dc.sourceWeb of Science
dc.titleEffects of a ferment soy product on the adipocyte area reduction and dyslipidemia control in hypercholesterolemic adult male ratsen
dc.typeArtigo
dcterms.licensehttp://www.biomedcentral.com/about/license
dcterms.rightsHolderBiomed Central Ltd.
unesp.author.lattes3242858535763793
unesp.author.lattes1730146818754269
unesp.author.lattes7641979287850489
unesp.author.orcid0000-0002-0084-3468[8]
unesp.author.orcid0000-0002-2257-078X[3]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Ciências Farmacêuticas, Araraquarapt

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Artigos - Alimentos e Nutrição - FCFAR
Artigos - Análises Clínicas - FCFAR