Report of cerebellar hypoplasia in three calves

dc.contributor.authorde Queiroz, Daniela Junqueira [UNESP]
dc.contributor.authorPenteado Dias, Deborah Martins [UNESP]
dc.contributor.authorCurtio Soares, Luciana Maria [UNESP]
dc.contributor.authorde Barros Bandarra, Marcio [UNESP]
dc.contributor.authorde Oliveira Vasconcelos, Rosemeri [UNESP]
dc.contributor.authorAlessi, Antonio Carlos [UNESP]
dc.contributor.authorCarlos Marques, Luiz [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:28:37Z
dc.date.available2014-05-27T11:28:37Z
dc.date.issued2013-03-01
dc.description.abstractHereditary or acquired cerebellar hypoplasia (CH) is commonly diagnosed in Holstein, Guernsey, Shorthorn and Jersey cattle. Bovine viral diarrhea (BVD) has been associated to acquired CH due to viral infection during the second trimester of pregnancy. Stricken calf usually shows ataxia, hypermetria, opisthotonus, intentional tremor and wide-based stance when in standing position. Three newborn calves were referred to the FCAV/Unesp Veterinary Teaching Hospital because of neurological distress. The clinical presentation, similar in all cases, indicated CH. Two weeks later, clinical signs did not improve and euthanasia was performed. Macroscopic examination revealed a gelatinous serosanguineous fluid over the brain surface and within the cervical spinal canal. Histologically the cerebellum had disorganization of the internal granular layer and moderate disappearance of Purkinje cells. The observed clinical signs and nervous tissue lesions were consistent with congenital cerebellar syndrome, possibly associated to viral infection during fetal development. Despite CH has been assumed to be related to BVD, blue tongue and Akabane viruses, only the BVD etiology has been already identified in Brazil.en
dc.description.affiliationDepartamento de Clínica e Cirurgia Veterinária Unesp, Jaboticabal, SP
dc.description.affiliationDepartamento de Patologia Veterinária Unesp, Jaboticabal, SP
dc.description.affiliationUnespDepartamento de Clínica e Cirurgia Veterinária Unesp, Jaboticabal, SP
dc.description.affiliationUnespDepartamento de Patologia Veterinária Unesp, Jaboticabal, SP
dc.format.extent26-30
dc.identifierhttp://www.abpv.vet.br/upload/documentos/DOWNLOAD-FULL-ARTICLE-08-20881_2013_4_16_19_55.pdf
dc.identifier.citationBrazilian Journal of Veterinary Pathology, v. 6, n. 1, p. 26-30, 2013.
dc.identifier.issn1983-0246
dc.identifier.lattes3281538474011979
dc.identifier.scopus2-s2.0-84877622527
dc.identifier.urihttp://hdl.handle.net/11449/74779
dc.language.isoeng
dc.relation.ispartofBrazilian Journal of Veterinary Pathology
dc.relation.ispartofsjr0,162
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectBovine viral diarrhea
dc.subjectCattle
dc.subjectCerebellar malformation
dc.subjectOpisthotonus
dc.titleReport of cerebellar hypoplasia in three calvesen
dc.typeArtigo
dcterms.licensehttp://www.abpv.vet.br/paginas_site/default.asp?P=BJVP&PAG_SEQ=4282
unesp.author.lattes3281538474011979
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Ciências Agrárias e Veterinárias, Jaboticabalpt

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