Specific components found in circulating immune complexes (CIC) in paracoccidioidomycosis

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dc.contributor.authorUnterkircher, C. S. [UNESP]
dc.contributor.authorYazaki, S. C. [UNESP]
dc.contributor.authorShimizu, M. T. [UNESP]
dc.contributor.authorJorge, A. O C [UNESP]
dc.contributor.authorCamargo, Z. P.
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversidade Federal de São Paulo (UNIFESP)
dc.date.accessioned2014-05-27T11:18:07Z
dc.date.available2014-05-27T11:18:07Z
dc.date.issued1996-10-19
dc.description.abstractCirculating immune complexes (CIC) from 15 paracoccidioidomycosis (PCM) patient sera and from 20 healthy control sera were analysed. After CIC precipitation, solubilization and acid treatment, only a little reactivity to P. brasiliensis antigens was found in the free antibodies from PCM-CIC. This result has suggested that there were antibodies with a high affinity bound to fungus components. Dissociated CIC were fractionated in a column of Sephacryl S300 and the fractions that probably contained antigens were pooled and applied to an affinity column, prepared with mouse anti-gp43 monoclonal antibody. Using ECL-Western blotting assay two polypeptide with apparent mass of 43 and 62 kDa were found.en
dc.description.affiliationSchool of Dentistry Deportment of Pathology São José Dos Campos, UNESP, São Paulo, SP
dc.description.affiliationUniversidade Federal de São Paulo Escola Paulista de Medicina, São Paulo, SP
dc.description.affiliationUniversidade Federal de São Paulo (UNIFESP) Escola Paulista de Medicina Disciplina de Biologia Celular, 04023-062, R. Botucatu 862/8 andar, São Paulo, SP
dc.description.affiliationUnespSchool of Dentistry Deportment of Pathology São José Dos Campos, UNESP, São Paulo, SP
dc.format.extent273-277
dc.identifierhttp://dx.doi.org/10.1080/02681219680000461
dc.identifier.citationJournal of Medical and Veterinary Mycology, v. 34, n. 4, p. 273-277, 1996.
dc.identifier.doi10.1080/02681219680000461
dc.identifier.issn0268-1218
dc.identifier.issn1369-3786
dc.identifier.issn1460-2709
dc.identifier.lattes0053567153623569
dc.identifier.scopus2-s2.0-0029792395
dc.identifier.scopus2-s2.0-79961158106
dc.identifier.urihttp://hdl.handle.net/11449/64865
dc.identifier.wosWOS:A1996VC30200007
dc.language.isoeng
dc.relation.ispartofJournal of Medical and Veterinary Mycology
dc.relation.ispartofjcr2.799
dc.relation.ispartofsjr0,973
dc.relation.ispartofsjr0,973
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectadult
dc.subjectaged
dc.subjectantibody affinity
dc.subjectantibody detection
dc.subjectantigen antibody complex
dc.subjectclinical article
dc.subjectfemale
dc.subjecthuman
dc.subjectimmunoblotting
dc.subjectmale
dc.subjectsouth american blastomycosis
dc.subjectAdult
dc.subjectAged
dc.subjectAnimals
dc.subjectAntibodies, Fungal
dc.subjectAntibodies, Monoclonal
dc.subjectAntigen-Antibody Complex
dc.subjectAntigens, Fungal
dc.subjectHumans
dc.subjectImmunoglobulin G
dc.subjectImmunoglobulin M
dc.subjectMice
dc.subjectMiddle Aged
dc.subjectParacoccidioidomycosis
dc.subjectReference Values
dc.subjectFungi
dc.subjectparacoccidioidomycosis brasiliensis
dc.titleSpecific components found in circulating immune complexes (CIC) in paracoccidioidomycosisen
dc.typeArtigo
dcterms.licensehttp://informahealthcare.com/userimages/ContentEditor/1255620309227/Copyright_And_Permissions.pdf
unesp.author.lattes0053567153623569[4]
unesp.author.orcid0000-0002-1747-6158[4]
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Ciência e Tecnologia, São José dos Campospt

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