Antiulcerogenic Compounds Isolated from Medicinal Plants

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dc.contributor.authorBeserra, Fernando Pereira [UNESP]
dc.contributor.authorRozza, Ariane Leite [UNESP]
dc.contributor.authorVieira, Ana Júlia [UNESP]
dc.contributor.authorSérgio Gushiken, Lucas Fernando [UNESP]
dc.contributor.authorPellizzon, Cláudia Helena [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2018-12-11T17:28:48Z
dc.date.available2018-12-11T17:28:48Z
dc.date.issued2016-01-01
dc.description.abstractThe gastric mucosa is continuously exposed to damaging agents that are involved in the pathogenesis of gastric ulcers, the most common chronic gastrointestinal disease. Common habits such as stress, coffee ingestion, tobacco, alcohol, and nonsteroidal antiinflammatory drugs' consumption contribute to the physiopathology of gastric ulcers. There is an ongoing search to discover novel bioactive gastroprotective and ulcer-healing compounds derived from medicinal plants. Among antiulcer studies using natural products, those focused on isolated compounds have brought promising results, which is important for developing new drugs against gastric ulcers. In this manuscript, we review the published antiulcer studies dedicated to isolated compounds, highlighting the chemical structure and mechanisms of action of each compound and trying to elucidate a structure-activity relationship for the tested compounds.en
dc.description.affiliationLaboratory of Natural Products Morphology Department Institute of Biosciences São Paulo State University (UNESP)
dc.description.affiliationUnespLaboratory of Natural Products Morphology Department Institute of Biosciences São Paulo State University (UNESP)
dc.format.extent215-234
dc.identifierhttp://dx.doi.org/10.1016/B978-0-444-63603-4.00006-1
dc.identifier.citationStudies in Natural Products Chemistry, v. 47, p. 215-234.
dc.identifier.doi10.1016/B978-0-444-63603-4.00006-1
dc.identifier.issn1572-5995
dc.identifier.lattes0019393779801069
dc.identifier.orcid0000-0002-4494-4180
dc.identifier.scopus2-s2.0-84976402812
dc.identifier.urihttp://hdl.handle.net/11449/178114
dc.language.isoeng
dc.relation.ispartofStudies in Natural Products Chemistry
dc.relation.ispartofsjr0,206
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectalkaloids
dc.subjectgastric ulcer
dc.subjectisolated compounds
dc.subjectphenolic compounds
dc.subjectsaponins
dc.subjectterpenes
dc.titleAntiulcerogenic Compounds Isolated from Medicinal Plantsen
dc.typeTrabalho apresentado em evento
unesp.author.lattes2328604224911233[2]
unesp.author.lattes0019393779801069[5]
unesp.author.orcid0000-0002-4198-0135[2]
unesp.author.orcid0000-0002-4494-4180[5]

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