Tissue reaction to Aroeira (Myracrodruon urundeuva) extracts associated with microorganisms: an in vivo study

Página do item simplificado
dc.contributor.authorBueno, Carlos Roberto Emerenciano
dc.contributor.authorValentim, Diego
dc.contributor.authorJardim Junior, Élerson Gaetti
dc.contributor.authorMancuso, Daniela Nardi
dc.contributor.authorSivieri-Araujo, Gustavo
dc.contributor.authorJacinto, Rogerio Castilho
dc.contributor.authorCintra, Luciano Tavares Angelo
dc.contributor.authorDezan-Junior, Eloi
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2018-12-11T17:24:15Z
dc.date.available2018-12-11T17:24:15Z
dc.date.issued2018-05-24
dc.description.abstractBased on aroeira's (Myracrodruon urundeuva) antimicrobial activity and a future trend to compose intracanal medication, the aim of this study was to assess in vivo inflamatory tissue response to the extracts by edemogenic and histological analysis containing inactivated facultative and anaerobic microorganisms. For edema quantification, eighteen animals were divided into three groups (n = 3, periods: 3 and 6 hours) and 0.2 mL of 1% Evans blue per 100 g of body weight was injected into the penile vein under general anesthesia. After 30 min the animals received a subcutaneous injection in the dorsal region of aqueous or ethanolic extract of aroeira or saline (control) containing inactivated bacteria. Samples were collected, immersed in formamide for 72h, and evaluated by spectrophotometry (630 m). For histological analysis, polyethylene tubes with the extracts were implanted in the dorsal of 30 male rats. Analysis of the fibrous capsule and inflammatory infiltrate were performed after 7 and 30 days. The aqueous extract group induced less edema in both postoperative periods compared to the other groups, but the differences were not significant (p > 0.05). Tissue repair was significantly better after 30 days than after 7 days (p < 0.01). The aqueous solution showed less inflammatory response than the ethanolic solution (p < 0.05), with tendency for better results than control after 7 days. After 30 days, the response to both extracts was similar to control. The aqueous and ethanolic aroeira extracts containing inactivated microorganisms showed a trend for better results than saline, even when associated with microorganisms, and facilitated the tissue repair process.en
dc.description.affiliationUniversidade Estadual Paulista- UNESP, Araçatuba School of Dentistry, Department of Endodontics, Araçatuba, SP, Brazil
dc.description.affiliationCentro Universitário do Distrito Federal - UDF, School of Dentistry, Department of Endodontics, Brasilia, DF, Brazil
dc.description.affiliationThe Specialist Endodontic Centre Emery & Mancuso, Portsmouth, United Kingdom
dc.format.extente42
dc.identifierhttp://dx.doi.org/10.1590/1807-3107bor-2018.vol32.0042
dc.identifier.citationBrazilian oral research, v. 32, p. e42-.
dc.identifier.doi10.1590/1807-3107bor-2018.vol32.0042
dc.identifier.fileS1806-83242018000100237.pdf
dc.identifier.issn1807-3107
dc.identifier.lattes9235743081667362
dc.identifier.lattes4605992512582464
dc.identifier.orcid0000-0002-6568-7734
dc.identifier.scieloS1806-83242018000100237
dc.identifier.scopus2-s2.0-85049248408
dc.identifier.urihttp://hdl.handle.net/11449/177157
dc.language.isoeng
dc.relation.ispartofBrazilian oral research
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.titleTissue reaction to Aroeira (Myracrodruon urundeuva) extracts associated with microorganisms: an in vivo studyen
dc.typeArtigo
unesp.author.lattes9235743081667362
unesp.author.lattes4605992512582464[3]

Arquivos

Pacote Original
Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
S1806-83242018000100237.pdf
Tamanho:
1.96 MB
Formato:
Adobe Portable Document Format
Baixar

Coleções

Artigos - Odontologia Restauradora - FOA