Detection of Epstein-Barr virus in different sources of materials from patients with oral lichen planus: a case-control study

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dc.contributor.authorVieira, Rubia da Rocha
dc.contributor.authorFerreira, Ligia Lavezo
dc.contributor.authorBiasoli, Eder Ricardo
dc.contributor.authorBernabe, Daniel Galera
dc.contributor.authorNunes, Caris Maroni
dc.contributor.authorMiyahara, Glauco Issamu
dc.contributor.institutionAracatuba Sch Dent
dc.contributor.institutionAracatuba Sch Vet Med
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2018-11-26T17:55:48Z
dc.date.available2018-11-26T17:55:48Z
dc.date.issued2016-04-01
dc.description.abstractAims To detect the presence of Epstein-Barr virus (EBV) DNA in different sources of materials from a matched group of patients with oral lichen planus (OLP) and a group of people without OLP lesions, and to correlate the presence of virus with epidemiological variables of the groups studied. Methods Fresh tissue samples, saliva, exfoliated cells and plasma of 24 patients with OLP lesions (cases) and 17 patients without OLP lesions (controls) were collected. EBV was detected by nested PCR. Results Viral positivity was obtained in 62.5% of tissue samples; in 70.8% of exfoliated cell samples; in 33.3% of blood plasma samples and in 75% of saliva samples in the cases; and in 35.3% of tissue samples; 82.4% of exfoliated cell samples; in 47.1% of blood plasma samples and in 64.7% of saliva samples in the controls. There was a predominance of women in both groups. Variables not atrophic-erosive were most affected by EBV. Conclusions No relationship between EBV and OLP was found. However, all sources tested in this study were considered suitable for the detection of viruses.en
dc.description.affiliationAracatuba Sch Dent, Oral Oncol Ctr, Aracatuba, SP, Brazil
dc.description.affiliationAracatuba Sch Dent, Dept Pathol & Clin Propaedeut, Aracatuba, SP, Brazil
dc.description.affiliationAracatuba Sch Vet Med, Anim Hlth & Prod, Aracatuba, SP, Brazil
dc.format.extent358-363
dc.identifierhttp://dx.doi.org/10.1136/jclinpath-2015-203325
dc.identifier.citationJournal Of Clinical Pathology. London: Bmj Publishing Group, v. 69, n. 4, p. 358-363, 2016.
dc.identifier.doi10.1136/jclinpath-2015-203325
dc.identifier.fileWOS000372466400012.pdf
dc.identifier.issn0021-9746
dc.identifier.lattes3846891167083211
dc.identifier.orcid0000-0002-5326-2026
dc.identifier.urihttp://hdl.handle.net/11449/164716
dc.identifier.wosWOS:000372466400012
dc.language.isoeng
dc.publisherBmj Publishing Group
dc.relation.ispartofJournal Of Clinical Pathology
dc.relation.ispartofsjr1,050
dc.rights.accessRightsAcesso aberto
dc.sourceWeb of Science
dc.titleDetection of Epstein-Barr virus in different sources of materials from patients with oral lichen planus: a case-control studyen
dc.typeArtigo
dcterms.rightsHolderBmj Publishing Group
unesp.author.lattes3846891167083211[3]
unesp.author.lattes1892359871207408[5]
unesp.author.orcid0000-0002-5545-3600[1]
unesp.author.orcid0000-0002-5326-2026[3]
unesp.author.orcid0000-0002-5463-3845[5]

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Araçatuba - COB - Centro de Oncologia Bucal
Artigos - Apoio, Produção e Saúde Animal - FMVA
Artigos - Patologia e Propedêutica Clínica - FOA