Role of Yersinia pseudotuberculosis outer proteins (Yops) in murine humoral immune response

Página do item simplificado
dc.contributor.authorMaia, J. M. L. [UNESP]
dc.contributor.authorMonnazzi, L. G. S. [UNESP]
dc.contributor.authorMedeiros, B. M. M.
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T13:24:11Z
dc.date.available2014-05-20T13:24:11Z
dc.date.issued2009-05-01
dc.description.abstractThe infection of mice with the wild-type (WT) strain of Y. pseudotuberculosis did not induce polyclonal activation of B lymphocytes. Suppression in the production of certain isotypes of Ig was observed, provoked mainly by YopH, YopJ and YpkA. The WT strain induced a progressive increase in the serum-specific IgG, which peaked after 4 weeks after infection, IgM being produced only after 1 week. Autoantibodies against phosphorylcholine, myelin, thyroglobulin and cardiolipin could be detected in the serum of mice infected with the WT strain. The infection of mice provoked suppression in the production of immunoglobulins by splenic B cells and that YopH, YopJ and YpkA must be involved here.en
dc.description.affiliationSão Paulo State Univ, Sch Pharmaceut Sci, Dept Biol Sci, Araraquara, SP, Brazil
dc.description.affiliationUnespSão Paulo State Univ, Sch Pharmaceut Sci, Dept Biol Sci, Araraquara, SP, Brazil
dc.description.sponsorshipPrograma de Apoio ao Desenvolvimento Científico da Faculdade de Ciências Farmacêuticas da UNESP (PADC)
dc.description.sponsorshipCoordena ao de Aperfei oamento de Pessoal de Nivel Superior, Brazil
dc.description.sponsorshipIdPADC: PADC 2004/6-I
dc.format.extent239-245
dc.identifierhttp://dx.doi.org/10.1007/s12223-009-0038-1
dc.identifier.citationFolia Microbiologica. Dordrecht: Springer, v. 54, n. 3, p. 239-245, 2009.
dc.identifier.doi10.1007/s12223-009-0038-1
dc.identifier.issn0015-5632
dc.identifier.urihttp://hdl.handle.net/11449/7435
dc.identifier.wosWOS:000268573600011
dc.language.isoeng
dc.publisherSpringer
dc.relation.ispartofFolia Microbiologica
dc.relation.ispartofjcr1.311
dc.relation.ispartofsjr0,502
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.titleRole of Yersinia pseudotuberculosis outer proteins (Yops) in murine humoral immune responseen
dc.typeArtigo
dcterms.licensehttp://www.springer.com/open+access/authors+rights?SGWID=0-176704-12-683201-0
dcterms.rightsHolderSpringer
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Ciências Farmacêuticas, Araraquarapt

Arquivos

Licença do Pacote
Agora exibindo 1 - 2 de 2
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:
Nenhuma Miniatura disponível
Nome:
license.txt
Tamanho:
1.71 KB
Formato:
Item-specific license agreed upon to submission
Descrição:

Coleções

Artigos - Ciências Biológicas - FCFAR