Serology of paracoccidioidomycosis - I. Evaluation of the indirect immunofluorescent test

dc.contributor.authorMistreta, Tania
dc.contributor.authorSouza, Maria Julia
dc.contributor.authorChamma, Luiz Gastão
dc.contributor.authorPinho, Sheila Zambello
dc.contributor.authorFranco, Marcello
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-26T23:43:21Z
dc.date.available2014-05-26T23:43:21Z
dc.date.issued1985-01-01
dc.description.abstractThe purposes of the present work were: i) to study the positivity indices and compare titers obtained with the indirect immunofluorescence (II), tube precipitation (TP), complement fixation (CF) and double immunodiffusion on agar gel (ID) tests in the sera of 196 patients with paracoccidioidomycosis before treatment, and ii) to compare the initial titers of II with those obtained 1 year or more after treatment. II was the most sensitive serologic reaction (85.2%), and the positivity indices for CF, ID and TP were 67.7%, 66.0% and 50.0%, respectively. The sera tended to show parallel mean titers in II, CF and TP tests. One year after treatment there was a fall in titers of II in 66.2% of patients. The data, taken as a whole, demonstrate the usefulness of the indirect immunofluorescent test and the importance of using 2 or more serologic tests for the diagnosis and monitoring of patients with paracoccidioidomycosis. © 1985 Martinus Nijhoff/Dr W. Junk Publishers.en
dc.description.affiliationDepartamento de Patologia Faculdade de Medicina, Botucatu, São Paulo, 18610
dc.format.extent13-17
dc.identifierhttp://dx.doi.org/10.1007/BF00437127
dc.identifier.citationMycopathologia, v. 89, n. 1, p. 13-17, 1985.
dc.identifier.doi10.1007/BF00437127
dc.identifier.issn0301-486X
dc.identifier.issn1573-0832
dc.identifier.scopus2-s2.0-0021925164
dc.identifier.urihttp://hdl.handle.net/11449/63702
dc.language.isoeng
dc.relation.ispartofMycopathologia
dc.relation.ispartofjcr1.476
dc.relation.ispartofsjr0,597
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectblood and hemopoietic system
dc.subjectclinical article
dc.subjectcomplement fixation
dc.subjectdiagnosis
dc.subjectfungus
dc.subjecthuman
dc.subjecthuman cell
dc.subjectimmunodiffusion
dc.subjectimmunofluorescence
dc.subjectmethodology
dc.subjectprecipitation test
dc.subjectsouth american blastomycosis
dc.subjectAntibodies, Fungal
dc.subjectComplement Fixation Tests
dc.subjectFluorescent Antibody Technique
dc.subjectFungi
dc.subjectHumans
dc.subjectImmunodiffusion
dc.subjectParacoccidioides
dc.subjectParacoccidioidomycosis
dc.subjectPrecipitin Tests
dc.subjectSerologic Tests
dc.titleSerology of paracoccidioidomycosis - I. Evaluation of the indirect immunofluorescent testen
dc.typeArtigo
dcterms.licensehttp://www.springer.com/open+access/authors+rights
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Biociências, Botucatupt

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