Recent mouse and rat methods for the study of experimental oral candidiasis

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dc.contributor.authorCosta, Anna C.B.P. [UNESP]
dc.contributor.authorPereira, Cristiane A. [UNESP]
dc.contributor.authorJunqueira, Juliana Campos [UNESP]
dc.contributor.authorJorge, Antonio O.C. [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionHans-Knoell-Institute
dc.date.accessioned2014-05-27T11:29:58Z
dc.date.available2014-05-27T11:29:58Z
dc.date.issued2013-07-17
dc.description.abstractThe Candida genus expresses virulence factors that, when combined with immunosuppression and other risk factors, can cause different manifestations of oral candidiasis. The treatment of mucosal infections caused by Candida and the elucidation of the disease process have proven challenging. Therefore, the study of experimentally induced oral candidiasis in rats and mice is useful to clarify the etiopathology of this condition, improve diagnosis, and search for new therapeutic options because the disease process in these animals is similar to that of human candidiasis lesions. Here, we describe and discuss new studies involving rat and mouse models of oral candidiasis with respect to methods for inducing experimental infection, methods for evaluating the development of experimental candidiasis, and new treatment strategies for oral candidiasis. © 2013 Landes Bioscience.en
dc.description.affiliationDepartment of Biosciences and Oral Diagnosis Institute of Science and Technology UNESP -Univ Estadual Paulista, São José dos Campos
dc.description.affiliationDepartment of Microbial Pathogenicity Mechanisms Hans-Knoell-Institute, Jena
dc.description.affiliationUnespDepartment of Biosciences and Oral Diagnosis Institute of Science and Technology UNESP -Univ Estadual Paulista, São José dos Campos
dc.format.extent391-399
dc.identifierhttp://dx.doi.org/10.4161/viru.25199
dc.identifier.citationVirulence, v. 4, n. 5, p. 391-399, 2013.
dc.identifier.doi10.4161/viru.25199
dc.identifier.file2-s2.0-84880078584.pdf
dc.identifier.issn2150-5594
dc.identifier.issn2150-5608
dc.identifier.lattes0322020541055900
dc.identifier.scopus2-s2.0-84880078584
dc.identifier.urihttp://hdl.handle.net/11449/75997
dc.identifier.wosWOS:000323324200007
dc.language.isoeng
dc.relation.ispartofVirulence
dc.relation.ispartofjcr3.947
dc.relation.ispartofsjr1,635
dc.relation.ispartofsjr1,635
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectCandida albicans
dc.subjectMurine model
dc.subjectOral candidiasis
dc.subjectOral cavity
dc.subjectamphotericin B
dc.subjectdexamethasone
dc.subjectfarnesol
dc.subjectfluconazole
dc.subjectlactoferrin
dc.subjecttetracycline
dc.subjectbacterial colonization
dc.subjectcolony forming unit
dc.subjectconfocal laser microscopy
dc.subjectdisease severity
dc.subjectepithelium hyperplasia
dc.subjectgene expression
dc.subjecthistopathology
dc.subjectimmunization
dc.subjectimmunocompromised patient
dc.subjectmuscle cell
dc.subjectnonhuman
dc.subjectphotodynamic therapy
dc.subjectrisk factor
dc.subjectSprague Dawley rat
dc.subjectthrush
dc.subjecttongue
dc.subjectWistar rat
dc.titleRecent mouse and rat methods for the study of experimental oral candidiasisen
dc.typeArtigo
dcterms.licensehttps://www.landesbioscience.com/user_agreement/
unesp.author.lattes0322020541055900
unesp.author.lattes0053567153623569[4]
unesp.author.orcid0000-0002-1747-6158[4]
unesp.campusUniversidade Estadual Paulista (Unesp), Instituto de Ciência e Tecnologia, São José dos Campospt

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