Effect of melatonin on the oxidative metabolism of colostrum phagocytes of diabetic women

dc.contributor.authorCalderon, Iracema de Mattos Paranhos [UNESP]
dc.contributor.authorMorceli, G. [UNESP]
dc.contributor.authorHara, C.
dc.contributor.authorVolpato, R.
dc.contributor.authorRudge, Marilza Vieira Cunha [UNESP]
dc.contributor.authorHonorio-Franca, A.
dc.contributor.authorFranca, E.
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-20T13:35:33Z
dc.date.available2014-05-20T13:35:33Z
dc.date.issued2011-01-01
dc.description.abstractAim: the aim of this study was verified the ability of melatonin hormone to modulate the oxidative metabolism of colostral phagocytes from diabetic mothers. Methods: based on 100g-OGTT and glucose profile analysis subjects were allocated into two groups: Non-diabetic (ND-10) and Diabetic (DM-8). Cells were separated by a Ficoll-Paque gradient and the oxidative metabolism was available thought superoxide release by colostrum phagocytes using the cytochrome C method. Results: melatonin hormone increased superoxide release by colostrum phagocytes of ND and decreased these release in colostrum phagocytes of DM mothers. Conclusion: the results suggest that the melatonin hormone can modulate the oxidative metabolism of phagocytes and an existence of relationship between control of glucose metabolism and melatonin action in colostrum phagocytes.en
dc.description.affiliationSão Paulo State Univ UNESP, Botucatu Med Sch, PG Program Gynecol Obstet & Mastol, São Paulo, Brazil
dc.description.affiliationUnespSão Paulo State Univ UNESP, Botucatu Med Sch, PG Program Gynecol Obstet & Mastol, São Paulo, Brazil
dc.format.extent139-142
dc.identifierhttp://www.monduzzieditore.it/shop/index.php?id_product=80&controller=product
dc.identifier.citation14th World Congress on Controversies In Obstetrics, Gynecology & Infertility (cogi). Bologna: Monduzzi Editore S P A, p. 139-142, 2011.
dc.identifier.lattes0679387622604743
dc.identifier.lattes6758680388835078
dc.identifier.orcid0000-0002-9227-832X
dc.identifier.urihttp://hdl.handle.net/11449/12244
dc.identifier.wosWOS:000313621800028
dc.language.isoeng
dc.publisherMonduzzi Editore S P A
dc.relation.ispartof14th World Congress on Controversies In Obstetrics, Gynecology & Infertility (cogi)
dc.rights.accessRightsAcesso aberto
dc.sourceWeb of Science
dc.subjectColostrumen
dc.subjectphagocytesen
dc.subjectsuperoxideen
dc.subjectmelatoninen
dc.subjectdiabetesen
dc.titleEffect of melatonin on the oxidative metabolism of colostrum phagocytes of diabetic womenen
dc.typeTrabalho apresentado em evento
dcterms.rightsHolderMonduzzi Editore S P A
unesp.author.lattes0679387622604743
unesp.author.lattes6758680388835078
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Medicina, Botucatupt

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