Cordia verbenacea DC. (Boraginaceae): quality control parameters, phytochemical screening and evaluation of anti-Candida activity
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Data
2016-01-01
Autores
Scardelato, J. A. [UNESP]
Santos, A. G. [UNESP]
Pietro, R. C.L.R. [UNESP]
Sacramento, L. V.S. [UNESP]
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Resumo
Cordia verbenacea occurs all along the Brazilian coast and it is widely used to treat various inflammatory processes. In the present study we aimed to describe a physical-chemical profile and pharmacognostic vegetal drug as well as to draw a chromatographic profile of the crude extract and its fractions. We have observed the occurrence of secondary metabolites such as flavonoids, terpenes and tannins. The study of anti-Candida activity of extracts indicated the best results for C. glabrata (9.77-36.06 μg.mL-1), intermediate values for C. krusei (312.5-625 μg.mL-1), C. tropicalis (312.5-625μg.mL-1) and high values for C. albicans (1250>2500 μg.mL-1) and C. parapsilosis 625-2500 μg.mL-1).
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anti-Candida, Cordia, phytochemical
Como citar
Revista Brasileira de Plantas Medicinais, v. 18, n. 4, p. 837-843, 2016.