Newcastle disease virus vaccine strains: Immunogenicity is not influenced by ICPI

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dc.contributor.authorOrsi, M. A.
dc.contributor.authorDoretto Júnior, L.
dc.contributor.authorReischak, D.
dc.contributor.authorda Silva, L. H. A.
dc.contributor.authorSpilki, F. R.
dc.contributor.authorBuzinaro, M. G. [UNESP]
dc.contributor.authorArns, C. W.
dc.contributor.institutionNational Agricultural Laboratory
dc.contributor.institutionUniversidade Estadual de Campinas (UNICAMP)
dc.contributor.institutionAvian Health Consultant
dc.contributor.institutionFeevale University Center
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2014-05-27T11:23:53Z
dc.date.available2014-05-27T11:23:53Z
dc.date.issued2009-04-01
dc.description.abstractIntracerebral pathogenicity index (ICPI) and mean death time (MDT) were determined using commercial live vaccines against Newcastle disease available in Brazil. The ICPI profiles obtained for B1 vaccine strains were nonvirulent and varied from 0 to 0.19, and their MDT was 104-116 hours. The LaSota strains had an ICPI varying between 0.02 and 0.37 and MDT from 92 to 116 hours. ICPI and MDT for the Clone 30 were 0.11 and 104 hours, respectively. For Ulster vaccines, ICPI and MDT were 0 and >150 hours; for VG-GA was 0.03 and 140 hours; and for C2, 0.04 and >144 hours. Eye drop vaccination and IM challenge, at the 1 st week and the 4 th week, respectively, resulted in highest protection for B1 (95-100%) and LaSota (90-100%) strains. The variability in vaccine ICPI did not interfere with immune response and all vaccines provided similar protection. All vaccines were considered non virulent and were classified as lentogenic according to the immunobiological product standards.en
dc.description.affiliationNational Agricultural Laboratory - Lanagro/ SP, Campinas, SP
dc.description.affiliationFaculty of Medical Sciences University of Campinas - Unicamp, Campinas, SP
dc.description.affiliationAvian Health Consultant
dc.description.affiliationFeevale University Center, Novo Hamburgo, RS
dc.description.affiliationDepartments of Preventive Medicine Faculty of Agricultural and Veterinary Sciences Paulista State University, Jaboticabal Campus, Jaboticabal, SP
dc.description.affiliationLaboratory of Virology Institute of Biology CP 6109, University of Campinas - Unicamp, 13083-970. Campinas, SP
dc.description.affiliationUnespDepartments of Preventive Medicine Faculty of Agricultural and Veterinary Sciences Paulista State University, Jaboticabal Campus, Jaboticabal, SP
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.format.extent129-133
dc.identifierhttp://dx.doi.org/10.1590/S1516-635X2009000200009
dc.identifier.citationRevista Brasileira de Ciencia Avicola, v. 11, n. 2, p. 129-133, 2009.
dc.identifier.doi10.1590/S1516-635X2009000200009
dc.identifier.file2-s2.0-70349432655.pdf
dc.identifier.issn1516-635X
dc.identifier.scieloS1516-635X2009000200009
dc.identifier.scopus2-s2.0-70349432655
dc.identifier.urihttp://hdl.handle.net/11449/70972
dc.identifier.wosWOS:000269654400009
dc.language.isoeng
dc.relation.ispartofRevista Brasileira de Ciência Avícola
dc.relation.ispartofjcr0.463
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectIntracerebral pathogenicity index (ICPI)
dc.subjectMean death time (MDT)
dc.subjectNewcastle disease virus (NDV) vaccines
dc.subjectAves
dc.subjectNewcastle disease virus
dc.titleNewcastle disease virus vaccine strains: Immunogenicity is not influenced by ICPIen
dc.typeArtigo
dcterms.licensehttp://www.scielo.br/revistas/rbca/paboutj.htm#03
unesp.author.orcid0000-0001-5804-7045[5]
unesp.author.orcid0000-0002-7308-460X[7]
unesp.campusUniversidade Estadual Paulista (Unesp), Faculdade de Ciências Agrárias e Veterinárias, Jaboticabalpt

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