Avaliação comparativa de segurança e eficácia para produtos de higiene íntima em mulheres na menopausa

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dc.contributor.authorSchalka, Sérgio
dc.contributor.authorBombarda, Patrícia Camarano Pinto [UNESP]
dc.contributor.authorJúnior, Mário Sérgio Bombarda [UNESP]
dc.contributor.authorDa Silva, Silvana Lima
dc.contributor.authorBueno, Priscila Tesini Brasil
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.contributor.institutionUniversidade Nove de Julho (UNINOVE)
dc.contributor.institutionMedcin Instituto da Pele Ltda
dc.date.accessioned2022-04-28T18:58:52Z
dc.date.available2022-04-28T18:58:52Z
dc.date.issued2013-10-01
dc.description.abstractBackground and objective: The menopause is the last menstrual period. A milestone in the climacteric, when major changes occurs in women's lives. The aim of this study was to evaluate the safety and efficacy in moisturizing and recovery of genital mucosa for hygiene products in menopause women. Method: Study involving 70 female volunteers, age 45 to 65 years, distributed in two groups of 35 members. Each group received one fragrance of the investigational product for 15 days and then was added a moisturizing lotion to the investigational product for more 15 days. After 7 days of wash-out period the volunteers used the comparative product for more 30 days. Evaluation of efficacy was performed by instrumental measurements as Transepidermal Water Loss (TEWL) and Corneometry. Subjective evaluations were performed through the questionnaires at the beginning and end of each treatment with the products. At the end of study, a questionnaire was answered comparing directly the treatments. Results: The comparative product showed better results, statistically significant, than the investigational product fragrance Silver Frutal in sensation of elasticity and firmness of the mucosa. The addition of the moisturizing lotion in both investigational products fragrances Silver Frutal and Floral brought positive results to all parameters evaluated, except to viscosity. As for the safety, none of the volunteers had allergic reaction or other adverse event. Conclusion: The hygiene products for the female genital region should preserve the physiological condi. © Copyright Moreira Jr. Editora.Todos os direitos reservados.en
dc.description.affiliationMedcin Instituto da Pele Ltda Faculdade de Medicina Universidade de São Paulo (USP), São Paulo SP
dc.description.affiliationMedcin Instituto da Pele Ltda Faculdade de Ciências Farmacêuticas Universidade Estadual Paulista (UNESP), Araraquara (SP)
dc.description.affiliationMedcin Instituto da Pele Ltda Instituto de Química Universidade Estadual Paulista (UNESP), Araraquara (SP)
dc.description.affiliationMedcin Instituto da Pele Ltda Faculdade de Farmácia e Bioquímica Universidade Nove de Julho (UNINOVE), São Paulo SP
dc.description.affiliationMedcin Instituto da Pele Ltda, Av. Dr. Carlos de Morais Barros, 304 Vila Campesina, CEP 06023-000 - Osasco - SP
dc.description.affiliationUnespMedcin Instituto da Pele Ltda Faculdade de Ciências Farmacêuticas Universidade Estadual Paulista (UNESP), Araraquara (SP)
dc.description.affiliationUnespMedcin Instituto da Pele Ltda Instituto de Química Universidade Estadual Paulista (UNESP), Araraquara (SP)
dc.identifier.citationRevista Brasileira de Medicina, v. 70, n. 10, 2013.
dc.identifier.issn0034-7264
dc.identifier.scopus2-s2.0-84887896252
dc.identifier.urihttp://hdl.handle.net/11449/219975
dc.language.isopor
dc.relation.ispartofRevista Brasileira de Medicina
dc.sourceScopus
dc.titleAvaliação comparativa de segurança e eficácia para produtos de higiene íntima em mulheres na menopausapt
dc.title.alternativeComparative evaluation of safety and efficacy for hygiene products in menopausal womenen
dc.typeArtigo

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