PCL/β-AgVO3 nanocomposites obtained by solvent casting as potential antimicrobial biomaterials

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dc.contributor.authorde Menezes, Beatriz Rossi Canuto
dc.contributor.authorMontanheiro, Thaís Larissa do Amaral
dc.contributor.authorSampaio, Aline da Graça [UNESP]
dc.contributor.authorKoga-Ito, Cristiane Yumi [UNESP]
dc.contributor.authorThim, Gilmar Patrocínio
dc.contributor.authorMontagna, Larissa Stieven
dc.contributor.institutionTechnological Institute of Aeronautics
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2021-06-25T11:06:00Z
dc.date.available2021-06-25T11:06:00Z
dc.date.issued2021-04-05
dc.description.abstractThe adhesion of microorganisms on biomaterials can impair its effective application. The addition of antimicrobial agents is a promising alternative to overcome this limitation. In this work, films of polycaprolactone (PCL) and nanostructured β-AgVO3 (SV) were produced by solvent casting with 0.1, 0.5, and 1.0 wt% of SV. The effect of SV on the structure of PCL was investigate using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Raman spectroscopy, differential scanning calorimetry (DSC), and scanning electron microscopy (SEM). The antimicrobial activity of the films against Staphylococcus aureus and Escherichia coli was evaluated by the agar diffusion method and by direct contact test. FTIR confirmed the presence of SV into the PCL films, with chemical interaction between them. SEM showed that SV nanorods were well dispersed and with good interfacial adhesion with PCL. XRD diffraction and Raman spectroscopy showed that the presence of SV increased the number of nucleation sites, reducing the size of crystallites and increasing the amorphous domains in the PCL matrix, consequently reducing crystallinity. This behavior was confirmed by DSC, which showed a reduction in the crystallinity with increasing SV content. Films with 1 wt% of SV showed antimicrobial activity against Staphylococcus aureus in direct contact test.en
dc.description.affiliationLaboratory of Plasmas and Processes Technological Institute of Aeronautics
dc.description.affiliationTechnology Laboratory of Polymers and Biopolymers Federal University of São Paulo
dc.description.affiliationGenoma Laboratory São José dos Campos Institute of Science and Technology São Paulo State University (UNESP)
dc.description.affiliationUnespGenoma Laboratory São José dos Campos Institute of Science and Technology São Paulo State University (UNESP)
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipFinanciadora de Estudos e Projetos
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipIdFinanciadora de Estudos e Projetos: 01.13.0328.03
dc.description.sponsorshipIdFAPESP: 2017/02846-5
dc.description.sponsorshipIdFAPESP: 2017/24873-4
dc.description.sponsorshipIdFAPESP: 2018/12035-7
dc.identifierhttp://dx.doi.org/10.1002/app.50130
dc.identifier.citationJournal of Applied Polymer Science, v. 138, n. 13, 2021.
dc.identifier.doi10.1002/app.50130
dc.identifier.issn1097-4628
dc.identifier.issn0021-8995
dc.identifier.lattes6543563161403421
dc.identifier.orcid0000-0002-2416-2173
dc.identifier.scopus2-s2.0-85094135354
dc.identifier.urihttp://hdl.handle.net/11449/208079
dc.language.isoeng
dc.relation.ispartofJournal of Applied Polymer Science
dc.sourceScopus
dc.subjectbiocompatibility
dc.subjectbiomedical applications
dc.subjectfilms
dc.subjectnanoparticles
dc.subjectnanowires and nanocrystals
dc.titlePCL/β-AgVO3 nanocomposites obtained by solvent casting as potential antimicrobial biomaterialsen
dc.typeArtigo
unesp.author.lattes6543563161403421[4]
unesp.author.orcid0000-0001-9605-3921[1]
unesp.author.orcid0000-0003-4230-8161[2]
unesp.author.orcid0000-0001-9453-3905[3]
unesp.author.orcid0000-0002-2416-2173[4]
unesp.author.orcid0000-0001-6410-3031[5]
unesp.author.orcid0000-0002-7947-3112[6]

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