Aerobic swimming training increases the activity of antioxidant enzymes and the glycogen content in the skeletal muscle of rats

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dc.contributor.authorVieira Junior, Roberto Carlos
dc.contributor.authorSantos Silva, Carolina Mendes
dc.contributor.authorde Araújo, Michel Barbosa [UNESP]
dc.contributor.authorGarcia, Alesandro
dc.contributor.authorVoltarelli, Vanessa Azevedo
dc.contributor.authordos Reis Filho, Adilson Domingos
dc.contributor.authorVoltarelli, Fabrício Azevedo
dc.contributor.institutionUFMT
dc.contributor.institutionUniversidade de São Paulo (USP)
dc.contributor.institutionUNIVAG - University Center
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.date.accessioned2022-04-28T18:58:31Z
dc.date.available2022-04-28T18:58:31Z
dc.date.issued2013-09-02
dc.description.abstractIntroduction: Studies which verified the effects of physical exercise on oxidative stress biomarkers and its relation to muscle glycogen are scant. Objective: The present study verified the effects of aerobic swimming training (AST) on biomarkers of oxidative stress, glycogen content and cell growth in the skeletal muscle of rats. Methods: Eighteen male Wistar rats (60 days) were divided into two groups: Sedentary Group (SG; n = 10): sedentary rats; and Trained Group (TG; n = 8): rats subjected to AST (5.0% of body weight), 1h/day, 5x/week, during 8 weeks. The activity of antioxidant enzymes (AOE) superoxide dismutase (SOD; U/ml), catalase (CAT; μmol/min/100mg), glutathione peroxidase (GPx; nmol/min/100mg), and substances that react with thiobarbituric acid levels (TBARs; nmolMDA/ mg protein) were determined in the right gastrocnemius muscle. Glycogen (mg/100mg), protein (g/100g), and DNA (g/100g) contents were evaluated in the left gastrocnemius muscle. Data were analyzed by Student t-test (p < 0.05). Results: AOE activity was higher in the TG group (CAT: 0.87 ± 0.04; SOD: 6.49 ± 0.45; GPX: 6.49 ± 0.52) when compared to SG group (CAT: 0.52 ± 0.03; SOD: 4.10 ± 0.37; GPx: 2.87 ± 0.35). TBARs levels was lower in TG (TG: 2.35 ± 0.45; SG: 8.90 ± 0.47). Gastrocnemius glycogen content (SG: 0.108 ± 0.013; TG: 0.320 ± 0.012) and protein/DNA ratio (SG: 24.94 ± 3.25; TG: 41.68 ± 4.02) were higher in TG group. Conclusion: Altogether, these data provide evidence that AST improved antioxidant defense, which may be associated to higher glycogen content of skeletal muscle of the animals.en
dc.description.affiliationUFMT, Cuiabá, MT
dc.description.affiliationPhysical Education and Sports School USP, São Paulo, SP
dc.description.affiliationUNIVAG - University Center, Várzea Grande, MT
dc.description.affiliationState University of São Paulo UNESP, Rio Claro, SP
dc.description.affiliationUnespState University of São Paulo UNESP, Rio Claro, SP
dc.format.extent204-208
dc.identifierhttp://dx.doi.org/10.1590/S1517-86922013000300012
dc.identifier.citationRevista Brasileira de Medicina do Esporte, v. 19, n. 3, p. 204-208, 2013.
dc.identifier.doi10.1590/S1517-86922013000300012
dc.identifier.issn1517-8692
dc.identifier.scopus2-s2.0-84883071899
dc.identifier.urihttp://hdl.handle.net/11449/219927
dc.language.isoeng
dc.relation.ispartofRevista Brasileira de Medicina do Esporte
dc.sourceScopus
dc.subjectCell proliferation
dc.subjectGlycogen
dc.subjectOxidative stress
dc.titleAerobic swimming training increases the activity of antioxidant enzymes and the glycogen content in the skeletal muscle of ratsen
dc.typeArtigo

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