Topical application of lidocaine or bupivacaine in the healing of surgical wounds in dogs

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dc.contributor.authorMinto, Bruno Watanabe [UNESP]
dc.contributor.authorZanato, Laura [UNESP]
dc.contributor.authorFranco, Guilherme Galhardo [UNESP]
dc.contributor.authorKawamoto, Fernando Yoiti Kitamura [UNESP]
dc.contributor.authorBorsaro, Camila Potério [UNESP]
dc.contributor.authorPazzini, Josiane Morais
dc.contributor.authorCarvalho, Elizabeth Regina [UNESP]
dc.contributor.authorMatsui, Andresa [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUnião das Faculdades dos Grandes Lagos (UNILAGO)
dc.date.accessioned2020-12-12T02:19:28Z
dc.date.available2020-12-12T02:19:28Z
dc.date.issued2020-01-01
dc.description.abstractPurpose: To analyze the anesthetic drugs interference with wound healing when used in the surgical bed. Methods: Macro and microscopic aspects of healing of surgical wounds were evaluated after instillation of topical anesthetics without vasoconstrictor or saline solution 0.9% as control in the transsurgical period. Thirty dogs, males and females were divided into two experimental groups. In both groups, two circular punch lesions of 6 mm diameter were performed in the abdomen. In group 1, lidocaine was instilled in one of the lesions and saline solution in the contralateral lesion. In group 2 the procedure was repeated with the use of bupivacaine. The macroscopic assessment of the lesions was performed on the first, third and tenth postoperative day. The excisional biopsy was performed on the tenth day and the samples were submitted for histopathological examination. Results: The macroscopic analysis had a significant difference between groups. Microscopic analysis was not significant between groups. Conclusions: The topical application of lidocaine and bupivacaine in the surgical wound is feasible and it does not influence skin healing. The benefit of such a practice, which has been the subject of other studies, seems to outweigh the risks.en
dc.description.affiliationDepartment of Clinical and Veterinary Surgery Faculdade de Ciências Agrárias e Veterinárias Universidade Estadual Paulista (FCAV-UNESP)
dc.description.affiliationFCAV-UNESP
dc.description.affiliationUnião das Faculdades dos Grandes Lagos (UNILAGO)
dc.description.affiliationUnespDepartment of Clinical and Veterinary Surgery Faculdade de Ciências Agrárias e Veterinárias Universidade Estadual Paulista (FCAV-UNESP)
dc.description.affiliationUnespFCAV-UNESP
dc.description.sponsorshipFundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
dc.description.sponsorshipIdFAPESP: 2015/24955-5
dc.format.extent1-8
dc.identifierhttp://dx.doi.org/10.1590/s0102-865020200070000001
dc.identifier.citationActa Cirurgica Brasileira, v. 35, n. 7, p. 1-8, 2020.
dc.identifier.doi10.1590/s0102-865020200070000001
dc.identifier.fileS0102-86502020000700202.pdf
dc.identifier.issn1678-2674
dc.identifier.issn0102-8650
dc.identifier.scieloS0102-86502020000700202
dc.identifier.scopus2-s2.0-85089551346
dc.identifier.urihttp://hdl.handle.net/11449/200915
dc.language.isoeng
dc.relation.ispartofActa Cirurgica Brasileira
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectAnalgesia
dc.subjectBupivacaine
dc.subjectDogs
dc.subjectLidocaine
dc.subjectSurgical Wounds
dc.titleTopical application of lidocaine or bupivacaine in the healing of surgical wounds in dogsen
dc.typeArtigo
unesp.author.lattes0131201084614247[1]
unesp.author.orcid0000-0002-8808-4127[1]

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Artigos - Clínica e Cirurgia Veterinária - FCAV