Chemical composition, antioxidant activity and development of a facial serum formulation from the extract of Hancornia speciosa

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dc.contributor.authorPanontin, Juliane Farinelli
dc.contributor.authorBarbosa, Robson dos Santos
dc.contributor.authorIsaac, Vera [UNESP]
dc.contributor.authorSeibert, Carla Simone
dc.contributor.authorScapin, Elisandra
dc.contributor.institutionFederal University of Tocantins
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)
dc.date.accessioned2022-04-28T19:52:45Z
dc.date.available2022-04-28T19:52:45Z
dc.date.issued2022-01-01
dc.description.abstractThe goal of this work was to chemically characterise Hancornia speciosa extracts to develop an antioxidant serum formulation. Stem and bark extracts were prepared using 70% hydroethanol solution by Sohxlet and ultrasound assisted extraction. The content of total phenols, flavonoids, and antioxidant activity were evaluated, and chemical characterization was performed by HPLC -detector UV-VIS (SPD − 10 A). The formulation was developed with stem extract (0.250 mg/g) in hydroxyethylcellulose fluid gel. Stem extracts had higher total phenols and flavonoids, and higher antioxidant activity than bark extracts. The formulation presented low viscosity, a yellowish colour, 81.28% ± 0.14 of antioxidant activity. In the stability test, the physicochemical characteristics showed small variations, remaining more stable at a temperature of 5 °C, with an antioxidant activity of 64.81% ± 0.75. Therefore, the stem of H. speciosa has the potential to be used in antioxidant formulations.en
dc.description.affiliationPostgraduate Program in Environmental Sciences–Ciamb Federal University of Tocantins, TO
dc.description.affiliationPostgraduate Program in Biodiversity and Biotechnology–BIONORTE Federal University of Tocantins, TO
dc.description.affiliationSchool of Pharmaceutical Sciences São Paulo State University (Unesp), SP
dc.description.affiliationUnespSchool of Pharmaceutical Sciences São Paulo State University (Unesp), SP
dc.identifierhttp://dx.doi.org/10.1080/14786419.2022.2053968
dc.identifier.citationNatural Product Research.
dc.identifier.doi10.1080/14786419.2022.2053968
dc.identifier.issn1478-6427
dc.identifier.issn1478-6419
dc.identifier.scopus2-s2.0-85127244209
dc.identifier.urihttp://hdl.handle.net/11449/223725
dc.language.isoeng
dc.relation.ispartofNatural Product Research
dc.sourceScopus
dc.subjectanti-ageing
dc.subjectDPPH
dc.subjectMangabeira
dc.subjectphenolic compounds
dc.subjectphytocosmetics
dc.titleChemical composition, antioxidant activity and development of a facial serum formulation from the extract of Hancornia speciosaen
dc.typeArtigo
unesp.author.orcid0000-0001-7402-920X[3]
unesp.author.orcid0000-0001-7506-308X[5]

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