L-(+)-Lactic acid production by Lactobacillus rhamnosus B103 from dairy industry waste

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dc.contributor.authorBernardo, Marcela Piassi [UNESP]
dc.contributor.authorCoelho, Luciana Fontes [UNESP]
dc.contributor.authorSass, Daiane Cristina [UNESP]
dc.contributor.authorContiero, Jonas [UNESP]
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2018-12-11T17:06:39Z
dc.date.available2018-12-11T17:06:39Z
dc.date.issued2016-07-01
dc.description.abstractLactic acid, which can be obtained through fermentation, is an interesting compound because it can be utilized in different fields, such as in the food, pharmaceutical and chemical industries as a bio-based molecule for bio-refinery. In addition, lactic acid has recently gained more interest due to the possibility of manufacturing poly(lactic acid), a green polymer that can replace petroleum-derived plastics and be applied in medicine for the regeneration of tissues and in sutures, repairs and implants. One of the great advantages of fermentation is the possibility of using agribusiness wastes to obtain optically pure lactic acid. The conventional batch process of fermentation has some disadvantages such as inhibition by the substrate or the final product. To avoid these problems, this study was focused on improving the production of lactic acid through different feeding strategies using whey, a residue of agribusiness. The downstream process is a significant bottleneck because cost-effective methods of producing high-purity lactic acid are lacking. Thus, the investigation of different methods for the purification of lactic acid was one of the aims of this work. The pH-stat strategy showed the maximum production of lactic acid of 143.7 g/L. Following purification of the lactic acid sample, recovery of reducing sugars and protein and color removal were 0.28%, 100% and 100%, respectively.en
dc.description.affiliationUNESP – Univ. Estadual Paulista Biological Sciences Institute Department of Biochemistry and Microbiology
dc.description.affiliationLaboratório Associado do IPBEN-Instituto de Pesquisa em Bioenergy da Unesp
dc.description.affiliationUnespUNESP – Univ. Estadual Paulista Biological Sciences Institute Department of Biochemistry and Microbiology
dc.description.affiliationUnespLaboratório Associado do IPBEN-Instituto de Pesquisa em Bioenergy da Unesp
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.format.extent640-646
dc.identifierhttp://dx.doi.org/10.1016/j.bjm.2015.12.001
dc.identifier.citationBrazilian Journal of Microbiology, v. 47, n. 3, p. 640-646, 2016.
dc.identifier.doi10.1016/j.bjm.2015.12.001
dc.identifier.fileS1517-83822016000300640.pdf
dc.identifier.issn1678-4405
dc.identifier.issn1517-8382
dc.identifier.scieloS1517-83822016000300640
dc.identifier.scopus2-s2.0-84991013977
dc.identifier.urihttp://hdl.handle.net/11449/173589
dc.language.isoeng
dc.relation.ispartofBrazilian Journal of Microbiology
dc.relation.ispartofsjr0,630
dc.rights.accessRightsAcesso aberto
dc.sourceScopus
dc.subjectFeed strategies
dc.subjectLactic acid production
dc.subjectLactobacillus and lactic acid purification
dc.titleL-(+)-Lactic acid production by Lactobacillus rhamnosus B103 from dairy industry wasteen
dc.typeArtigo

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