Cardiorespiratory fitness and risk of all-cause, cardiovascular disease, and cancer mortality in men with musculoskeletal conditions

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dc.contributor.authorLemes, Ítalo Ribeiro [UNESP]
dc.contributor.authorSui, Xuemei
dc.contributor.authorFritz, Stacy L.
dc.contributor.authorBeattie, Paul F.
dc.contributor.authorLavie, Carl J.
dc.contributor.authorTuri-Lynch, Bruna Camilo [UNESP]
dc.contributor.authorBlair, Steven N.
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.contributor.institutionUniversity of South Carolina
dc.contributor.institutionUniversity of Queensland School of Medicine
dc.date.accessioned2019-10-06T15:31:39Z
dc.date.available2019-10-06T15:31:39Z
dc.date.issued2019-02-01
dc.description.abstractBackground: To investigate the association between cardiorespiratory fitness and risk of cardiovascular disease, cancer, and all-cause mortality in men with musculoskeletal conditions. Methods: Participants were 12,728 men (mean age 47.0 [9.3] y) with a history of musculoskeletal conditions (including joint pain, low back pain, stiff joints, arthritis, osteoporosis, or gout) and were followed for all-cause mortality to December 31, 2003. Fitness was quantified by maximal treadmill exercise test and was categorized for analysis as low, moderate, and high performance. Cox proportional hazards regression was used to calculate hazard ratios and 95% confidence intervals. Results: Overall, the multivariable-adjusted hazard ratios and 95% confidence intervals for mortality across incremental fitness categories were 1.00 (reference), 0.45 (0.30–0.68) and 0.35 (0.22–0.53), linear trend P < .01 for all-cause, 0.50 (0.23–1.10) and 0.29 (0.12–0.71), linear trend P = .02 for cardiovascular disease, and 0.38 (0.20–0.74) and 0.40 (0.20–0.80), linear trend P = .01 for cancer mortality. Conclusion: Among men with musculoskeletal conditions, higher fitness is associated with lower risk of death by cardiovascular disease, cancer, or any cause, independent of other risk factors.en
dc.description.affiliationDepartment of Physical Therapy Faculty of Sciences and Technology São Paulo State University (UNESP)
dc.description.affiliationDepartment of Exercise Science Arnold School of Public Health University of South Carolina
dc.description.affiliationDepartment of Cardiovascular Diseases John Ochsner Heart and Vascular Institute Ochsner Clinical School University of Queensland School of Medicine
dc.description.affiliationDepartment of Physical Education Institute of Biosciences São Paulo State University (UNESP)
dc.description.affiliationUnespDepartment of Physical Therapy Faculty of Sciences and Technology São Paulo State University (UNESP)
dc.description.affiliationUnespDepartment of Physical Education Institute of Biosciences São Paulo State University (UNESP)
dc.format.extent134-140
dc.identifierhttp://dx.doi.org/10.1123/jpah.2017-0644
dc.identifier.citationJournal of Physical Activity and Health, v. 16, n. 2, p. 134-140, 2019.
dc.identifier.doi10.1123/jpah.2017-0644
dc.identifier.issn1543-5476
dc.identifier.issn1543-3080
dc.identifier.scopus2-s2.0-85060539901
dc.identifier.urihttp://hdl.handle.net/11449/187291
dc.language.isoeng
dc.relation.ispartofJournal of Physical Activity and Health
dc.rights.accessRightsAcesso restrito
dc.sourceScopus
dc.subjectBone and joint condition
dc.subjectCohort study
dc.subjectDeath
dc.subjectExercise capacity
dc.titleCardiorespiratory fitness and risk of all-cause, cardiovascular disease, and cancer mortality in men with musculoskeletal conditionsen
dc.typeArtigo

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