Effect of age and sex on bone markers in Chlorocebus aethiops raised in captivity

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dc.contributor.authorImbeloni, Aline Amaral
dc.contributor.authorRahal, Sheila Canevese [UNESP]
dc.contributor.authorSilva Filho, Ednaldo da
dc.contributor.authorFaria, Bianca Mendonca
dc.contributor.authorSilva, Wellington Bandeira da
dc.contributor.authorOliveira, Karol Guimaraes
dc.contributor.authorAihara, Mika Ester
dc.contributor.authorBarros Monteiro, Frederico Ozanan
dc.contributor.institutionMinist Saude
dc.contributor.institutionUniv Fed Rural Amazonia
dc.contributor.institutionUniversidade Estadual Paulista (Unesp)
dc.date.accessioned2018-11-26T16:19:24Z
dc.date.available2018-11-26T16:19:24Z
dc.date.issued2016-02-01
dc.description.abstractBackgroundThe objective was to evaluate the procollagen type I N-propeptide (PINP), osteocalcin (OC), -crosslaps (-CTX), and parathyroid hormone (PTH) in relation to age and sex of Chlorocebus aethiops in captivity. MethodsSeventy-three monkeys were divided into four age groups: AG1 (juvenile); AG2 (young adult); AG3 (adult); and AG4 (senile). An electrochemiluminescence immunoassay with an Elecsys 2010 analyzer was used to determine the serum markers of bone. Results and conclusionsSex did not influence the results of the markers. However, the variables PINP, OC, and -CTX were negatively correlated with age (r = -0.643; r = -0.711; r = -0.488; P < 0.001, respectively), and PTH was correlated positively with age (r = 0.418, P < 0.001). The data obtained can be used as biomarkers of bone metabolism reference intervals in healthy C. aethiops in captivity.en
dc.description.affiliationMinist Saude, Ctr Nacl Primatas, Secretaria Vigilancia Saude, Ananindeua, PA, Brazil
dc.description.affiliationUniv Fed Rural Amazonia, Programa Posgrad Saude & Prod Anim Amazonia, BR-66077901 Belem, PA, Brazil
dc.description.affiliationUniv Estadual Paulista, Fac Med Vet Zootecnia, Dept Cirurgia Vet & Anestesiol, Botucatu, SP, Brazil
dc.description.affiliationUnespUniv Estadual Paulista, Fac Med Vet Zootecnia, Dept Cirurgia Vet & Anestesiol, Botucatu, SP, Brazil
dc.description.sponsorshipNational Primate Center (CENP)
dc.description.sponsorshipCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
dc.description.sponsorshipConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
dc.description.sponsorshipIdCAPES: 21/2009
dc.description.sponsorshipIdCAPES: 06/2011
dc.description.sponsorshipIdCNPq: 1/2012
dc.format.extent3-11
dc.identifierhttp://dx.doi.org/10.1111/jmp.12201
dc.identifier.citationJournal Of Medical Primatology. Hoboken: Wiley, v. 45, n. 1, p. 3-11, 2016.
dc.identifier.doi10.1111/jmp.12201
dc.identifier.issn0047-2565
dc.identifier.urihttp://hdl.handle.net/11449/161168
dc.identifier.wosWOS:000369066600001
dc.language.isoeng
dc.publisherWiley-Blackwell
dc.relation.ispartofJournal Of Medical Primatology
dc.relation.ispartofsjr0,365
dc.rights.accessRightsAcesso restrito
dc.sourceWeb of Science
dc.subjectbone formation markers of bone resorption markers
dc.subjectCercopithecidae
dc.subjectprimates
dc.titleEffect of age and sex on bone markers in Chlorocebus aethiops raised in captivityen
dc.typeArtigo
dcterms.licensehttp://olabout.wiley.com/WileyCDA/Section/id-406071.html
dcterms.rightsHolderWiley-Blackwell

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Artigos - Anestesiologia - FMB