Now showing items 1-10 of 93
Oxidative DNA damage in patients infected by Helicobacter pylori
(Ii Intercontinental Congress of Pathology, 2004-01-01) [Trabalho apresentado em evento]
Farming technology, biochemistry characterization, and protective effects of culinary-medicinal mushrooms Agaricus brasiliensis S. Wasser et al. and Lentinus edodes (Berk.) Singer: Five years of research in Brazil
(International Journal of Medicinal Mushrooms, 2005-07-04) [Artigo]
The biotechnology, biochemical characterization, and protective effects of the himematsutake and shiitake mushrooms were studied for the Thematic Project, from 1998 to 2003. A new species, Agaricus Brasiliens is Wasser et ...
Biocompatibility in vitro tests of mineral trioxide aggregate and regular and white Portland cements
(Journal of Endodontics, 2005-08-01) [Artigo]
Mineral trioxide aggregate (MTA) and Portland cement are being used in dentistry as root end-filling materials. However, biocompatibility data concerning genotoxicity and cytotoxicity are needed for complete risk assessment ...
Genotoxicity in primary human peripheral lymphocytes after exposure to regular and white mineral trioxide aggregate
(Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology, 2006-11-01) [Artigo]
Objective: Taking into consideration that DNA damage plays an important role in carcinogenesis, the purpose of this study was to evaluate whether regular and white mineral trioxide aggregate (MTA) are able to induce genetic ...
Evaluation of DNA damage and lipoperoxidation of propofol in patients undergoing elective surgery
(European Journal of Anaesthesiology, 2009-08-01) [Artigo]
Background and objectives Inhaled anaesthetics have been studied regarding their genotoxic and mutagenic potential in vivo. Propofol differs from volatile anaesthetics because it does not show mutagenic effects and it has ...
DNA damage and aberrant crypt foci as putative biomarkers to evaluate the chemopreventive effect of annatto (Bixa orellana L.) in rat colon carcinogenesis
(Mutation Research: Genetic Toxicology and Environmental Mutagenesis, 2005-04-04) [Artigo]
Chemoprevention opens new perspectives in the prevention of cancer and other degenerative diseases. Use of target-organ biological models at the histological and genetic levels can markedly facilitate the identification ...
Effect of Helicobacter pylori infection on IL-8, IL-1 and COX-2 expression in patients with chronic gastritis and gastric cancer
(Scandinavian Journal of Gastroenterology, 2009-01-01) [Artigo]
Objective. Helicobacter pylori infection is related to gastric cancer development, and chronic inflammation is presumed to be the main cause. The aim of the present study was to evaluate the influence of H. pylori cagA, ...
Viable human buccal mucosa cells do not yield typical nucleoids: Impacts on the single-cell gel electrophoresis/comet assay
(Environmental and Molecular Mutagenesis, 2006-03-01) [Artigo]
Buccal mucosa (BM) cells have been used in human biomonitoring studies for detecting DNA adducts and chromosomal damage in an epithelial cell population. In the present study, we have investigated if human BM cells are ...
Aberrant crypt foci and colon cancer: comparison between a short- and medium-term bioassay for colon carcinogenesis using dimethylhydrazine in Wistar rats
(Brazilian Journal of Medical and Biological Research, 2002-03-01) [Artigo]
Aberrant crypt foci (ACF) in the colon of carcinogen-treated rodents are considered to be the earliest hallmark of colon carcinogenesis. In the present study the relationship between a short-term (4 weeks) and medium-term ...
Lack of genotoxicity of formocresol, paramonochlorophenol, and calcium hydroxide on mammalian cells by comet assay
(Journal of Endodontics, 2004-08-01) [Artigo]
Formocresol, paramonochlorophenol, and calcium hydroxide are widely used in dentistry because of their antibacterial activities in root canal disinfection. However, the results of genotoxicity studies using these materials ...